J
Jean François Germond
Researcher at University of Lausanne
Publications - 4
Citations - 882
Jean François Germond is an academic researcher from University of Lausanne. The author has contributed to research in topics: Dosimeter & Mucositis. The author has an hindex of 4, co-authored 4 publications receiving 404 citations.
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Journal ArticleDOI
The Advantage of FLASH Radiotherapy Confirmed in Mini-pig and Cat-cancer Patients.
Marie-Catherine Vozenin,Pauline de Fornel,Kristoffer Petersson,Vincent Favaudon,Maud Jaccard,Jean François Germond,Benoit Petit,Marco Burki,Gisele Ferrand,David Patin,Hanan Bouchaab,Mahmut Ozsahin,François Bochud,Claude Bailat,Patrick Devauchelle,Jean Bourhis +15 more
TL;DR: The results confirmed the potential advantage of FLASH-RT and provide a strong rationale for further evaluating FLash-RT in human patients.
Journal ArticleDOI
Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species.
Pierre Montay-Gruel,Munjal M. Acharya,Kristoffer Petersson,Leila Alikhani,Chakradhar Yakkala,Barrett D. Allen,Jonathan Ollivier,Benoit Petit,Patrik Gonçalves Jorge,Amber R. Syage,Thuan Nguyen,Al Anoud D. Baddour,Celine Lu,Paramvir Singh,Raphaël Moeckli,François Bochud,Jean François Germond,Pascal Froidevaux,Claude Bailat,Jean Bourhis,Marie-Catherine Vozenin,Charles L. Limoli +21 more
TL;DR: The remarkable normal tissue sparing afforded by FLASH may someday provide heretofore unrealized opportunities for dose escalation to the tumor bed, capabilities that promise to hasten the translation of this groundbreaking irradiation modality into clinical practice.
Journal ArticleDOI
Hypofractionated FLASH-RT as an Effective Treatment against Glioblastoma that Reduces Neurocognitive Side Effects in Mice.
Pierre Montay-Gruel,Munjal M. Acharya,Patrik Gonçalves Jorge,Benoit Petit,Ioannis G. Petridis,Philippe Fuchs,Ron Leavitt,Kristoffer Petersson,Maude Gondré,Jonathan Ollivier,Raphaël Moeckli,François Bochud,Claude Bailat,Jean Bourhis,Jean François Germond,Charles L. Limoli,Marie-Catherine Vozenin +16 more
TL;DR: The present results show that FLASH-RT delivered with hypofractionated regimens is able to spare the normal brain from radiation-induced toxicities without compromising tumor cure, and provides an initial framework for future clinical applications of FLash-RT.
Journal ArticleDOI
Dosimetric and preparation procedures for irradiating biological models with pulsed electron beam at ultra-high dose-rate.
Patrik Gonçalves Jorge,Maud Jaccard,Kristoffer Petersson,Maude Gondré,Maria Teresa Durán,Laurent Desorgher,Jean François Germond,Philippe Liger,Marie-Catherine Vozenin,Jean Bourhis,François Bochud,Raphaël Moeckli,Claude Bailat +12 more
TL;DR: The method is based on validated absolute dosimeters and extends their use to routine FLASH irradiations and developed the requirements needed for workflows of preclinical and clinical studies.