J
Jean T. Corbett
Researcher at National Institutes of Health
Publications - 46
Citations - 1979
Jean T. Corbett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Phthalate & Radical. The author has an hindex of 26, co-authored 46 publications receiving 1890 citations.
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Journal ArticleDOI
Pharmacokinetics, interactions with macromolecules and species differences in metabolism of DEHP.
TL;DR: Radioactivity from carbonyl-labeled DEHP did not associate with purified protein, RNA or DNA from rat liver in vivo, and the apparent binding from DEHP and MEHP was not exchangeable, but was not proven to be covalent.
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In vivo lipid-derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS
Keizo Sato,Maria B. Kadiiska,Andrew J. Ghio,Jean T. Corbett,Yang C. Fann,Steven M. Holland,Ronald G. Thurman,Ronald P. Mason +7 more
TL;DR: In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide is investigated, using rats treated with intratracheal instillation of LPS as a model for ARDS.
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Quantitative characterization of polychlorinated biphenyl mixtures (aroclors® 1248, 1254 and 1260) by gas chromatograpy using capillary columns
TL;DR: In this article, the polychlorinated biphenyl (PCB) compositions of Aroclors 1248, 1254 and 1260 have been determined using gas chromatography.
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Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis.
Saurabh Chatterjee,Douglas Ganini,Erik J. Tokar,Ashutosh Kumar,Suvarthi Das,Jean T. Corbett,Maria B. Kadiiska,Michael P. Waalkes,Anna Mae Diehl,Ronald P. Mason +9 more
TL;DR: Results, for the first time, suggest that leptin action in macrophages of the steatotic liver, through induction of iNOS and NADPH oxidase, causes peroxynitrite-mediated oxidative stress thus activating Kupffer cells.
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on lipid profiles in tissue of the Fischer rat.
TL;DR: A rapid, dose-dependent effect of TCDD, was the elevation of levels of organic-soluble fluorescent pigment in the heart, which was found to match a previously characterized fraction of lipofuscins in fluorescence spectrum and chromatographic properties.