J
Jeanne M. Lusher
Researcher at Wayne State University
Publications - 201
Citations - 10115
Jeanne M. Lusher is an academic researcher from Wayne State University. The author has contributed to research in topics: Haemophilia & Haemophilia A. The author has an hindex of 55, co-authored 201 publications receiving 9722 citations. Previous affiliations of Jeanne M. Lusher include Detroit Medical Center & Boston Children's Hospital.
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Journal ArticleDOI
Definitions in hemophilia. Recommendation of the scientific subcommittee on factor VIII and factor IX of the scientific and standardization committee of the International Society on Thrombosis and Haemostasis.
Gilbert C. White,Frits R. Rosendaal,Louis M. Aledort,Jeanne M. Lusher,Chantal Rothschild,Jørgen Ingerslev +5 more
TL;DR: Definitions in Hemophilia - Recommendation of the Scientific Subcommittee on Factor VIII and Factor IX and the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis.
Journal ArticleDOI
Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group.
TL;DR: Transient or low levels of inhibitor, as observed in this study, may represent part of the natural history of hemophilia in infants and the benefits of recombinant factor VIII for the treatment of hemophile seem to outweigh the risks.
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Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors
Nigel S. Key,Louis M. Aledort,D Beardsley,H A Cooper,G. Davignon,Bruce M. Ewenstein,Gerald S. Gilchrist,Joan Cox Gill,Bertil Glader,W K Hoots,C. T. Kisker,Jeanne M. Lusher,Cathy G. Rosenfield,Amy D. Shapiro,H Smith,E Taft +15 more
TL;DR: In this paper, the authors evaluated the safety and efficacy of a fixed dose of recombinant activated factor VII (rFVIIa) in the home setting for mild to moderately severe joint, muscle, and mucocutaneous bleeding episodes in patients with haemophilia A or B with inhibitors.
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Diminished helper/suppressor lymphocyte ratios and natural killer activity in recipients of repeated blood transfusions.
TL;DR: It is suggested that a modest decrease in T4/T8 ratio and NK activity may be part of the normal immune response to repeated transfusion.