J
Jeannette Y. Lee
Researcher at University of Arkansas for Medical Sciences
Publications - 252
Citations - 15678
Jeannette Y. Lee is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Population & Cancer. The author has an hindex of 62, co-authored 242 publications receiving 14651 citations. Previous affiliations of Jeannette Y. Lee include Fred Hutchinson Cancer Research Center & National Institutes of Health.
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Journal ArticleDOI
Potent suppression of hiv-1 replication in humans by t-20, a peptide inhibitor of gp41-mediated virus entry
J M Kilby,S Hopkins,T M Venetta,B DiMassimo,Gretchen A. Cloud,Jeannette Y. Lee,L Alldredge,Eric Hunter,D. M. Lambert,Dani P. Bolognesi,T J Matthews,M R Johnson,Martin A. Nowak,George M. Shaw,Michael S. Saag +14 more
TL;DR: Proof-of-concept that viral entry can be successfully blocked in vivo is provided, and short-term administration of T-20 seems safe and provides potent inhibition of HIV replication comparable to anti-retroviral regimens approved at present.
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A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients.
Peter G. Pappas,John H. Rex,Jeannette Y. Lee,Richard J. Hamill,Robert A. Larsen,William G. Powderly,Carol A. Kauffman,Newton E. Hyslop,Julie E. Mangino,Stanley W. Chapman,Harold W. Horowitz,John E. Edwards,William E. Dismukes +12 more
TL;DR: Subjects in the observational cohort had higher Acute Physiology and Chronic Health Evaluation II scores than did participants in the clinical trial, which suggests that the former subjects are more often excluded from therapeutic trials.
Journal ArticleDOI
Antifungal Susceptibility Survey of 2,000 Bloodstream Candida Isolates in the United States
Luis Ostrosky-Zeichner,John H. Rex,Peter G. Pappas,Richard J. Hamill,Robert A. Larsen,Harold W. Horowitz,William G. Powderly,Newton E. Hyslop,Carol A. Kauffman,John D. Cleary,Julie E. Mangino,Jeannette Y. Lee +11 more
TL;DR: Although no established interpretative breakpoints are available for the candins (CFG, MFG, and AFG) and the new azoles (VOR and POS), they all exhibited excellent antifungal activity, even for those strains resistant to the other aforementioned agents.
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A Randomized and Blinded Multicenter Trial of High-Dose Fluconazole plus Placebo versus Fluconazole plus Amphotericin B as Therapy for Candidemia and Its Consequences in Nonneutropenic Subjects
John H. Rex,John H. Rex,Peter G. Pappas,Adolf W. Karchmer,Jack D. Sobel,John E. Edwards,Susan Hadley,Corstiaan Brass,Jose A. Vazquez,Stanley W. Chapman,Harold W. Horowitz,Marcus J. Zervos,David S. McKinsey,Jeannette Y. Lee,Timothy Babinchak,Robert W. Bradsher,John D. Cleary,David M. Cohen,Larry H. Danziger,Mitchell Goldman,Jesse L. Goodman,Eileen Hilton,Newton E. Hyslop,Daniel H. Kett,Jon E. Lutz,Robert H. Rubin,W. Michael Scheld,Mindy G. Schuster,Bryan P. Simmons,David K. Stein,Ronald G. Washburn,Linda Mautner,Teng-Chiao Chu,Helene Panzer,Rebecca B. Rosenstein,Jenia Booth +35 more
TL;DR: In nonneutropenic subjects, the combination of fluconazole plus AmB was not antagonistic compared with flu Conazole alone, and the combination trended toward improved success and more-rapid clearance from the bloodstream.
Journal ArticleDOI
A Randomized Trial of Itraconazole in Allergic Bronchopulmonary Aspergillosis
David A. Stevens,H. J. Schwartz,Jeannette Y. Lee,Bruce L. Moskovitz,D. C. Jerome,Antonino Catanzaro,David M. Bamberger,A. J. Weinmann,C. U. Tuazon,Marc A. Judson,Thomas A.E. Platts-Mills,A. C. DeGraff +11 more
TL;DR: For patients with corticosteroid-dependent allergic bronchopulmonary aspergillosis, the addition of itraconazole can lead to improvement in the condition without added toxicity.