J
Jeff Boyd
Researcher at Florida International University
Publications - 70
Citations - 13881
Jeff Boyd is an academic researcher from Florida International University. The author has contributed to research in topics: Tumor suppressor gene & Gene. The author has an hindex of 42, co-authored 69 publications receiving 13229 citations. Previous affiliations of Jeff Boyd include Research Triangle Park & University of Pennsylvania.
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Journal Article
The search for BRCA1.
Lori Friedman,Elizabeth A. Ostermeyer,Eric D. Lynch,Csilla Szabo,Lee A. Anderson,Patrick Dowd,Ming K. Lee,Sarah Rowell,Jeff Boyd,Mary Claire King +9 more
TL;DR: BRCA1, a gene predisposing to breast and ovarian cancer, was mapped to chromosome 17q21 by linkage analysis and revealed 44 variants, including two missense mutations in two genes which segregated with breast cancer and were not found in controls, however, no frame-shift, nonsense, or regulatory mutations were found.
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Expression and mutation analysis of the p53 gene in uterine papillary serous carcinoma
Stephanie A. King,Amy A. Adas,Virginia A. LiVolsi,Hiroyuki Takahashi,Kian Behbakht,B S Patricia McGovern,Ivor Benjamin,Stephen C. Rubin,Jeff Boyd +8 more
TL;DR: The status of p53 protein expression was determined by immunohistochemistry and correlated with genetic analysis and clinical outcome in patients with uterine papillary serous carcinoma (UPSC) as discussed by the authors.
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22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors.
Lori Friedman,Elizabeth A. Ostermeyer,Eric D. Lynch,Piri Welcsh,Csilla Szabo,Jose E. Meza,Lee A. Anderson,Patrick Dowd,Ming K. Lee,Sarah Rowell,Jay Ellison,Jeff Boyd,Mary Claire King +12 more
TL;DR: In the effort to identify BRCA1, 22 genes were cloned from a 1-Mb region of chromosome 17q21 defined by meiotic recombinants in families with inherited breast and/or ovarian cancer, and 36 polymorphic variants were observed in both cases and controls.
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Analysis of oncogene alterations in human endometrial carcinoma: prevalence of ras mutations.
Jeff Boyd,John I. Risinger +1 more
TL;DR: The data suggest that the amplification or overexpression of several proto‐oncogenes frequently observed in other human gynecologic and breast tumors are not prevalent in endometrial carcinoma and that ras gene mutations are relatively common in this tumor type.
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Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias.
Matthew F. Kohler,Hiroshi Nishii,Peter A. Humphrey,Hiroshi Saski,Jeffrey R. Marks,Robert C. Bast,Daniel L. Clarke-Pearson,Jeff Boyd,Andrew Berchuck +8 more
TL;DR: Because it does not appear to be a feature of endometrial hyperplasias, mutation of the p53 gene may represent a relatively late event inendometrial carcinogenesis.