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Jefferson A. Vaughan

Researcher at University of North Dakota

Publications -  57
Citations -  1835

Jefferson A. Vaughan is an academic researcher from University of North Dakota. The author has contributed to research in topics: Population & Anopheles gambiae. The author has an hindex of 23, co-authored 53 publications receiving 1632 citations. Previous affiliations of Jefferson A. Vaughan include United States Department of the Army & Johns Hopkins University.

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Ookinete rates in Afrotropical anopheline mosquitoes as a measure of human malaria infectiousness.

TL;DR: Relationships between human malaria infectiousness and vector infectivity are dependent upon the high efficiency of the developmental transition from the ookinete to the subsequent oocyst and sporozoite stages.
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Dual host infections: enhanced infectivity of eastern equine encephalitis virus to Aedes mosquitoes mediated by Brugia microfilariae.

TL;DR: It is suggested that certain key parameters determine whether dual virus/mf host infections will enhance arboviral infectivity to mosquitoes, including species differences in the capacity of mf to penetrate the mosquito midgut, the amount of virus passing into the hemocoel during mf penetration, and the innate susceptibility of mosquitoes to hemocoelsomically introduced virus.
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Presence of calreticulin in vector fleas (Siphonaptera).

TL;DR: The results show that fleas have calreticulin and, possibly, several isoforms, and it appears that the salivary glands of the cat and oriental rat flea differ in detectable levels of cal reticulin.
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Brugia malayi microfilariae (Nematoda: Filaridae) enhance the infectivity of Venezuelan equine encephalitis virus to Aedes mosquitoes (Diptera: Culicidae).

TL;DR: The contrasting effects of microfilarial enhancement of viral infectivity and MF-induced mortality in mosquitoes differed among mosquito species and were determined by the nature and consequences of MF penetration through the mosquito midgut, but not to differences in mosquito susceptibilities to parenterally introduced virus.
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Plasmodium falciparum: the population structure of mature gametocyte cultures has little effect on their innate fertility.

TL;DR: If a reliable parasite isolate or clone is used, there is no need to measure other characteristics of in vitro gametocyte populations because these will not significantly improve one's ability to predict oocyst infection rates.