J
Jeffrey Aubé
Researcher at University of North Carolina at Chapel Hill
Publications - 423
Citations - 10202
Jeffrey Aubé is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Schmidt reaction & Azide. The author has an hindex of 52, co-authored 396 publications receiving 8853 citations. Previous affiliations of Jeffrey Aubé include Sanford-Burnham Institute for Medical Research & Duke University.
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MAIT cells are imprinted by the microbiota in early life and promote tissue repair
Michael G. Constantinides,Verena M. Link,Samira Tamoutounour,Andrea C. Wong,P. Juliana Perez-Chaparro,Seong-Ji Han,Y. Erin Chen,Kelin Li,Sepideh Farhat,Antonin Weckel,Siddharth R. Krishnamurthy,Ivan Vujkovic-Cvijin,Jonathan L. Linehan,Nicolas Bouladoux,E. Dean Merrill,Sobhan Roy,Daniel J. Cua,Erin J. Adams,Avinash Bhandoola,Tiffany C. Scharschmidt,Jeffrey Aubé,Michael A. Fischbach,Yasmine Belkaid +22 more
TL;DR: How the microbiota can direct immune cell development and subsequent function at mucosal sites by secreting compounds that act like self-antigens is highlighted by highlighting how the bacteria and fungi can direct tissue repair functions by promoting the maturation and homeostasis of the immune system.
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The internal quaternary ammonium receptor site of Shaker potassium channels
TL;DR: Quaternary ammonium (QA) compounds inhibit K+ conductance by entering and occluding the open pore of voltage-activated K+ channels and several mutations in the P region affect tetraethylammonium binding but have minimal effects on longer blockers, suggesting that the hydrophobic tail contributes to binding in a nonadditive fashion.
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Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies
Giovanni M. Pauletti,Giovanni M. Pauletti,Sanjeev Gangwar,Teruna J. Siahaan,Jeffrey Aubé,Ronald T. Borchardt +5 more
TL;DR: This manuscript will focus on the physiological limitations for oral peptide delivery and on various strategies using chemical modifications to improve oral bioavailability of peptide-based drugs.
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Chemistry of Bridged Lactams and Related Heterocycles
Michal Szostak,Jeffrey Aubé +1 more
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Intramolecular Schmidt Reaction of Alkyl Azides
Jeffrey Aubé,Gregory L. Milligan +1 more