J
Jeffrey J. Rade
Researcher at University of Massachusetts Medical School
Publications - 70
Citations - 6497
Jeffrey J. Rade is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Thromboxane & Platelet. The author has an hindex of 24, co-authored 68 publications receiving 5733 citations. Previous affiliations of Jeffrey J. Rade include Johns Hopkins University School of Medicine & University of Massachusetts Amherst.
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Journal ArticleDOI
Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress
Ilan S. Wittstein,David R. Thiemann,Joao A.C. Lima,Kenneth L. Baughman,Steven P. Schulman,Gary Gerstenblith,Katherine C. Wu,Jeffrey J. Rade,Trinity J. Bivalacqua,Hunter C. Champion +9 more
TL;DR: Emotional stress can precipitate severe, reversible left ventricular dysfunction in patients without coronary disease andaggerated sympathetic stimulation is probably central to the cause of this syndrome.
Journal ArticleDOI
Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States During COVID-19 Pandemic.
Santiago Garcia,Mazen Albaghdadi,Perwaiz Meraj,Christian W. Schmidt,Ross Garberich,Farouc A. Jaffer,Simon R. Dixon,Jeffrey J. Rade,Mark Tannenbaum,Jenny Chambers,Paul P Huang,Timothy D. Henry +11 more
TL;DR: The COVID-19 pandemic has significantly affected the U.S. health care system and the Centers for Disease Control and Prevention recommended deferral of elective cardiac procedures.
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A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina
Cindy L. Grines,Matthew W. Watkins,John J. Mahmarian,Ami E. Iskandrian,Jeffrey J. Rade,Pran Marrott,Craig M. Pratt,Neal S. Kleiman +7 more
TL;DR: Intracoronary injection of Ad5FGF-4 showed an encouraging trend for improved myocardial perfusion; however, further studies of therapeutic angiogenesis with Ad 5F GF-4 will be necessary.
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Focal modification of electrical conduction in the heart by viral gene transfer
J. Kevin Donahue,Alan W. Heldman,Heather Fraser,Amy D. McDonald,Julie M. Miller,Jeffrey J. Rade,Thomas Eschenhagen,Eduardo Marbán +7 more
TL;DR: The results demonstrate the feasibility of using myocardial gene transfer strategies to treat common arrhythmias and hypothesized that excess Gαi2 would mimic the effects of β-adreneric antagonists, in effect creating a localized β-blockade.
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In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries.
TL;DR: It is concluded that adenoviral vector-mediated gene transfer into the injured rat carotid artery results in efficient geneTransfer into the vascular media, with levels of recombinant protein production significantly higher than any previously reported in arterial gene transfer studies.