J
Jeffrey M. Peters
Researcher at Pennsylvania State University
Publications - 217
Citations - 21665
Jeffrey M. Peters is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Peroxisome proliferator-activated receptor & Receptor. The author has an hindex of 74, co-authored 214 publications receiving 20405 citations. Previous affiliations of Jeffrey M. Peters include Lawrence Livermore National Laboratory & National Institutes of Health.
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Journal ArticleDOI
Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid.
Pei-Li Yao,David J. Ehresman,Jessica Caverly Rae,Shu Ching Chang,Steven R. Frame,John L. Butenhoff,Gerald L. Kennedy,Jeffrey M. Peters +7 more
TL;DR: The data indicate that PFOA does not activate mouse or human ER, and treatment of a stable human cell line containing an ER-dependent luciferase reporter construct with a broad concentration range of P FOA caused no change in ER- dependent luciferases activity.
Journal ArticleDOI
Effect of arsenite and cadmium ions on xanthine oxidase.
Jeffrey M. Peters,D.R. Sanadi +1 more
TL;DR: The results are inconclusive regarding the involvement of dithiol groups in xanthine oxidase, but 2,3-Dimercaptopropanol inhibits the activity strongly while cadmium ion is inert at levels which inhibit other known dathiol enzymes.
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Current Challenges and Recent Developments in Mass Spectrometry-Based Metabolomics.
TL;DR: A review of liquid chromatography-mass spectrometry-based methods for metabolomics can be found in this article, which highlights important instrumentational, experimental, and computational tools that have been created to address these challenges and how they have enabled the advancement of metabolomics research.
Journal ArticleDOI
A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)
Salvatore Genovese,Jennifer E. Foreman,Michael G. Borland,Francesco Epifano,Frank J. Gonzalez,Massimo Curini,Jeffrey M. Peters +6 more
TL;DR: Results from these studies demonstrate that compound 1 can activate PPARbeta/delta and inhibit cell proliferation of a human skin cancer cell line, suggesting that the biological effects of 4'-geranyloxyferulic acid may be mediated in part by activating this PPAR isoform.
PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.
Mayur Choudhary,Jindong Ding,Xiaoping Qi,Michael E. Boulton,Pei-Li Yao,Jeffrey M. Peters,Goldis Malek +6 more
TL;DR: In this article, the impact of PPARβ/δ activation on ocular tissues affected by age-related macular degeneration (AMD) was investigated, with the goal of identifying signaling pathways that may be important in the development of AMD.