J
Jeffrey M. Peters
Researcher at Pennsylvania State University
Publications - 217
Citations - 21665
Jeffrey M. Peters is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Peroxisome proliferator-activated receptor & Receptor. The author has an hindex of 74, co-authored 214 publications receiving 20405 citations. Previous affiliations of Jeffrey M. Peters include Lawrence Livermore National Laboratory & National Institutes of Health.
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Journal ArticleDOI
Diminished Hepatocarcinogenesis by a Potent, High-Affinity Human PPARα Agonist in PPARA-Humanized Mice.
Jennifer E. Foreman,Takayuki Koga,Oksana Kosyk,Boo Hyon Kang,Xiaoyang Zhu,Samuel M. Cohen,Laura J. Billy,Arun Sharma,Shantu Amin,Frank J. Gonzalez,Ivan Rusyn,Jeffrey M. Peters +11 more
TL;DR: In this paper, the authors examined the effect of long-term administration of a potent, high-affinity human PPARα agonist (GW7647) on hepatocarcinogenesis in wild-type, Ppara-null, or PPARA-humanized mice.
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Enhancing effect of maternal zinc deficiency and 137Cs γ‐irradiation on the frequency of fetal malformations in mice
TL;DR: GD8 irradiation during maternal Zn deficiency had an additive effect on the frequency of fetal malformations, and groups fed the low Zn diet through GD5 or GD10 had lower mean maternal body weights, fewer live fetuses/litter, and a higher incidence of resorptions than controls.
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Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype.
TL;DR: It is demonstrated that PPARβ/δ is an important regulator of mast cell phenotype, and the production of cytokines by mast cells induced by various stimuli was highly dependent on PPAR βδ expression.
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Effect of a metallothionein antisense oligonucleotide on embryo development.
TL;DR: Combined work shows that an antisense ODN against MT can significantly affect blastocyst formation of preimplantation embryos; some, but not all, of the observed effects on embryo cell number may have been due to nucleotide toxicity.
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Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis
TL;DR: The focus of this review is on the fundamental level of PPARβ/δ expression in normal tissues and cancerous tissue as described by studies during the past two decades and what has been delineated during this timeframe about how PPAR β/ δ expression influences carcinogenesis, with an emphasis on colon cancer.