J
Jemima J. Burden
Researcher at University College London
Publications - 66
Citations - 3374
Jemima J. Burden is an academic researcher from University College London. The author has contributed to research in topics: Synaptic vesicle & Biology. The author has an hindex of 28, co-authored 53 publications receiving 2575 citations. Previous affiliations of Jemima J. Burden include Imperial College London.
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Journal ArticleDOI
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves
Anne-Laure Cattin,Jemima J. Burden,Lucie Van Emmenis,Francesca E. Mackenzie,Julian J.A. Hoving,Noelia Garcia Calavia,Yan-Ping Guo,Maeve McLaughlin,Laura H. Rosenberg,Victor Quereda,Denisa Jamecna,Ilaria Napoli,Simona Parrinello,Tariq Enver,Christiana Ruhrberg,Alison C. Lloyd +15 more
TL;DR: It is shown that blood vessels direct the migrating cords of Schwann cells, which use the blood vessels as "tracks" to cross a ‘bridge’ of new tissue, which forms to reconnect a severed nerve.
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Cdc42, Par6, and aPKC Regulate Arp2/3-Mediated Endocytosis to Control Local Adherens Junction Stability
TL;DR: A novel role is revealed for the epithelial polarity machinery, Cdc42-aPKC-Par6- aPKC, in local AJ remodeling through the control of Arp2/3-dependent endocytosis in local Drosophila notum development.
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The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration
Melanie Clements,Elizabeth Byrne,Luis F. Camarillo Guerrero,Anne-Laure Cattin,Leila Zakka,Azhaar Ashraf,Jemima J. Burden,Sanjay Khadayate,Alison C. Lloyd,Samuel Marguerat,Simona Parrinello +10 more
TL;DR: The wound microenvironment is a key determinant of Schwann cell identity, and it promotes nerve repair through integration of multiple concerted signals.
Journal ArticleDOI
The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling.
Eric Schonteich,Gayle M. Wilson,Jemima J. Burden,Colin R. Hopkins,Keith Anderson,James R. Goldenring,Rytis Prekeris +6 more
TL;DR: It is proposed that the Rip11/FIP5-kinesin-II complex has a key role in the routing of internalized receptors through the perinuclear recycling endosomes.
Journal ArticleDOI
A vesicle superpool spans multiple presynaptic terminals in hippocampal neurons
Kevin Staras,Tiago Branco,Jemima J. Burden,Karine Pozo,Kevin J Darcy,Vincenzo Marra,Arjuna Ratnayaka,Yukiko Goda +7 more
TL;DR: A vesicle pool that is not confined to a synapse but spans multiple terminals is demonstrated, and the involvement of a local TrkB-receptor-dependent mechanism for synapse-specific regulation of presynaptic vESicle pools through control of vesicles release and capture to or from the extrasynaptic pool is suggested.