B
Buzz Baum
Researcher at University College London
Publications - 165
Citations - 10944
Buzz Baum is an academic researcher from University College London. The author has contributed to research in topics: Mitosis & Cell division. The author has an hindex of 49, co-authored 150 publications receiving 9119 citations. Previous affiliations of Buzz Baum include Curie Institute & Howard Hughes Medical Institute.
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Journal ArticleDOI
Dynamics of adherens junctions in epithelial establishment, maintenance, and remodeling
Buzz Baum,Marios Georgiou +1 more
TL;DR: This work has shown that E-cadherin is actively turned over at junctions and contributes to junction formation and to the maintenance of epithelial integrity during tissue homeostasis and remodeling.
Journal ArticleDOI
Minimizing the risk of reporting false positives in large-scale RNAi screens
C Echeverri,Philip A. Beachy,Buzz Baum,Michael Boutros,Frank Buchholz,Sumit K. Chanda,Julian Downward,Jan Ellenberg,Andrew G. Fraser,Nir Hacohen,Nir Hacohen,William C. Hahn,William C. Hahn,Aimee L. Jackson,Amy A. Kiger,Peter S. Linsley,Lawrence G. Lum,Yong Ma,Bernard Mathey-Prevot,David E. Root,David M. Sabatini,Jussi Taipale,Norbert Perrimon,Norbert Perrimon,René Bernards +24 more
TL;DR: This Commentary is an invitation to an open discussion started among various users of RNAi to set forth accepted standards that would insure the quality and accuracy of information in the large datasets coming out of genome-scale screens.
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A functional genomic analysis of cell morphology using RNA interference
TL;DR: Using RNAi, genes that influence cytoskeletal organization and morphology in two distinct cell types are identified and proposed to propose similar functions for previously uncharacterized genes.
Journal ArticleDOI
Transitions between epithelial and mesenchymal states in development and disease.
TL;DR: The molecular and cellular mechanisms underpinning EMT are both an essential feature of Metazoan development and an important area of biomedical research.
Journal ArticleDOI
Moesin Controls Cortical Rigidity, Cell Rounding, and Spindle Morphogenesis during Mitosis
TL;DR: Data show that changes in the activity and localization of Moesin that accompany mitotic progression contribute to the establishment of a stiff, rounded cortex at metaphase and to polar relaxation at anaphase and reveal the importance of this MoesIn-induced increase in cortical rigidity for spindle morphogenesis and orderly chromosome segregation.