J
Jennifer E. Layden
Researcher at University of Illinois at Chicago
Publications - 17
Citations - 3252
Jennifer E. Layden is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Life expectancy & Viral load. The author has an hindex of 12, co-authored 16 publications receiving 3139 citations.
Papers
More filters
Journal ArticleDOI
A Potential Decline in Life Expectancy in the United States in the 21st Century
S. Jay Olshansky,Douglas J. Passaro,Ronald C. Hershow,Jennifer E. Layden,Bruce A. Carnes,Jacob A. Brody,Leonard Hayflick,Robert N. Butler,David B. Allison,David S. Ludwig +9 more
TL;DR: From an analysis of the effect of obesity on longevity, it is concluded that the steady rise in life expectancy during the past two centuries may soon come to an end.
Journal ArticleDOI
Timing of susceptibility-based antifungal drug administration in patients with Candida bloodstream infection: correlation with outcomes
Shellee A. Grim,Karen Berger,Christine B Teng,Sandeep Gupta,Jennifer E. Layden,William M. Janda,Nina M. Clark +6 more
TL;DR: Candida bloodstream infection is associated with high mortality, despite timely receipt of appropriate antifungal therapy, despite the impact of timing on patient survival.
Journal ArticleDOI
First phase viral kinetic parameters as predictors of treatment response and their influence on the second phase viral decline.
Jennifer E. Layden,Thomas J. Layden,K. Rajender Reddy,Rachel S. Levy-Drummer,Jennifer J. Poulakos,Avidan U. Neumann +5 more
TL;DR: Results suggest that early viral kinetics may predict lack of response after only 24’h of treatment initiation and indicate a strong link between the degree of viral load reduction during the first phase, and the subsequent 2nd phase decline slope.
Journal ArticleDOI
A Potential Decline in Life Expectancy in the United States in the 21st Century
S. Jay Olshansky,Douglas J. Passaro,Ronald C. Hershow,Jennifer E. Layden,Bruce A. Carnes,Jacob A. Brody,Leonard Hayflick,Robert N. Butler,David B. Allison,David S. Ludwig +9 more
TL;DR: Estimates of future life expectancy strongly influence public policy on age-based entitlement programs such as Social Security and Medicare, and the authors believe that current trends in life expectancy are likely to increase.
Journal ArticleDOI
Mathematical modeling of viral kinetics: a tool to understand and optimize therapy.
TL;DR: In a rather short time, the study of viral kinetics has improved our understanding of HCV infection, especially in relation to treatment response as discussed by the authors, which has been used to challenge the way we treat patients, understand the difference between nonresponders and responders, gain insight into possible mechanisms of treatment resistance, and predict treatment response.