J
Jennifer E. Van Eyk
Researcher at Cedars-Sinai Medical Center
Publications - 461
Citations - 25039
Jennifer E. Van Eyk is an academic researcher from Cedars-Sinai Medical Center. The author has contributed to research in topics: Medicine & Proteome. The author has an hindex of 77, co-authored 412 publications receiving 20853 citations. Previous affiliations of Jennifer E. Van Eyk include Johns Hopkins University School of Medicine & University of British Columbia.
Papers
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Journal ArticleDOI
Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0.
Eric W. Deutsch,Lydie Lane,Christopher M. Overall,Nuno Bandeira,Mark S. Baker,Charles Pineau,Robert L. Moritz,Fernando J. Corrales,Sandra Orchard,Jennifer E. Van Eyk,Young Ki Paik,Susan T. Weintraub,Yves Vandenbrouck,Gilbert S. Omenn,Gilbert S. Omenn +14 more
TL;DR: An update to the HPP MS Data Interpretation Guidelines is described based on consensus-reaching discussions with the wider HPP community over the past year and the revised 3.0 guidelines address several major and minor identified gaps.
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Assessment of albumin removal from an immunoaffinity spin column: critical implications for proteomic examination of the albuminome and albumin-depleted samples.
Rebekah L. Gundry,Melanie Y. White,Melanie Y. White,Julie Nogee,Irina Tchernyshyov,Jennifer E. Van Eyk +5 more
TL;DR: The data presented in the current work illustrate the difficulty in completely removing albumin from the immunoaffinity device, and consequently, may explain the variability and decreased efficiency shown for this device in previous studies.
Journal ArticleDOI
Characterization of the cardiac myosin binding protein-C phosphoproteome in healthy and failing human hearts
TL;DR: The most highly phosphorylated site on cMyBP-C was Ser284 and this site showed decreased phosphorylation in the failing heart, which implicates importance for fine-tuning contractility.
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Cofilin-2 phosphorylation and sequestration in myocardial aggregates: novel pathogenetic mechanisms for idiopathic dilated cardiomyopathy.
Khaushik Subramanian,Davide Gianni,Cristina Balla,Gabriele Egidy Assenza,Mugdha Joshi,Marc J. Semigran,Thomas E. MacGillivray,Jennifer E. Van Eyk,Giulio Agnetti,Nazareno Paolocci,James R. Bamburg,Pankaj B. Agrawal,Federica del Monte +12 more
TL;DR: This study provides the first biochemical characterization of prefibrillar myocardial aggregates in humans and the first report to link cofilin-2 to cardiomyopathy, suggesting a common pathogenetic mechanism connecting certain iDCMs and other chronic degenerative diseases.
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National Heart, Lung, and Blood Institute Clinical Proteomics Working Group Report
TL;DR: The National Heart, Lung, and Blood Institute (NHLBI) Clinical Proteomics Working Group was charged with identifying opportunities and challenges in clinical proteomics and using these as a basis for recommendations aimed at directly improving patient care as discussed by the authors.