J
Jennifer R. Sage
Researcher at University of California, San Diego
Publications - 16
Citations - 2122
Jennifer R. Sage is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Fear conditioning & Memory consolidation. The author has an hindex of 14, co-authored 14 publications receiving 1971 citations. Previous affiliations of Jennifer R. Sage include University of California, Los Angeles.
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Journal ArticleDOI
Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice
Robert M. Mihalek,Pradeep K. Banerjee,Esa R. Korpi,Joseph J. Quinlan,Leonard L. Firestone,Zhi Ping Mi,Carl F. Lagenaur,Verena Tretter,Werner Sieghart,Stephan G. Anagnostaras,Jennifer R. Sage,Michael S. Fanselow,Alessandro Guidotti,Igor Spigelman,Zhiwei Li,Timothy M. DeLorey,Richard W. Olsen,Gregg E. Homanics +17 more
TL;DR: The results begin to illuminate the novel contributions of the delta subunit to GABA pharmacology and sedative/hypnotic responses and behavior and provide insights into the physiology of neurosteroids.
Journal ArticleDOI
Role of the basolateral amygdala in the storage of fear memories across the adult lifetime of rats.
Greg D. Gale,Stephan G. Anagnostaras,Bill P. Godsil,Shawn Mitchell,Takashi Nozawa,Jennifer R. Sage,Brian J. Wiltgen,Michael S. Fanselow +7 more
TL;DR: Findings indicate that BLA lesions do not disrupt freezing behavior by producing hyperactivity, an inability to suppress behavior, or an unable to freeze, and the consistent pattern of freezing deficits at both training-to-lesion intervals supports a role for the BLA in the permanent storage of fear memory.
Journal ArticleDOI
Context fear learning in the absence of the hippocampus.
Brian J. Wiltgen,Matthew J. Sanders,Stephan G. Anagnostaras,Jennifer R. Sage,Michael S. Fanselow +4 more
TL;DR: The results demonstrate that alternative systems can acquire context fear but do so less efficiently than the hippocampus, and that animals with complete hippocampus lesions could also learn about the context, although the same lesions produced devastating retrograde amnesia.
Journal ArticleDOI
Psychostimulants and Cognition: A Continuum of Behavioral and Cognitive Activation
TL;DR: A continuum of psychostimulant activation that covers the transition from one drug effect to another as stimulant intake is increased is proposed, which helps account for the seemingly disparate effects of stimulant drugs.
Journal ArticleDOI
Automated assessment of pavlovian conditioned freezing and shock reactivity in mice using the video freeze system.
Stephan G. Anagnostaras,Suzanne C. Wood,Tristan Shuman,Denise J. Cai,Arthur D LeDuc,Karl R Zurn,J. Brooks Zurn,Jennifer R. Sage,Gerald M. Herrera +8 more
TL;DR: An extensive validation of the Video Freeze system in mice is reported, a “turn-key” all-inclusive system for fear conditioning in small animals using digital video and near-infrared lighting, which achieved outstanding performance in scoring both freezing and movement.