There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

Phd by thesis

https://pubs.rsc.org/en/content/articlepdf/2019/NP/C8NP00092A

Marine natural products.

The study was funded by Spanish projects BIO2005-03569, AGL2005-01748 and CTQ2005-08925-C02-02, EU project QLK3-99-590, and ENCE-CSIC contracts. Beldem (Andenne, Belgium) is acknowledged for the laccase sample.

/pdf/chemical-characterization-of-eucalypt-pulp-lignin-during-x4f5h6oy8e.pdf

Chemical characterization of eucalypt pulp lignin during totally chlorine free bleaching including a laccase-mediator stage: 2D-NMR, FTIR and Py-GC/MS of enzymatically-isolated residual lignins.

/pdf/oral-treatment-with-iododiflunisal-delays-beta-amyloid-2hjb492xo8.pdf

Oral treatment with iododiflunisal delays beta amyloid plaque formation in a transgenic mouse model of Alzheimer Disease: a Longitudinal in vivo molecular imaging study

https://chemistry-europe.onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201190041

Corrigendum: Carbohydrate–Protein Interactions: A 3D View by NMR

This article focuses on the applications of carbohydrate molecules in medicinal and pharmaceutical chemistry. Particular emphasis has been paid to these glycans that are currently used in the market with different properties. In particular, we have highlighted the role of glycans in cancer, in metabolic diseases, or in the immune response, also emphasizing those glycans that display properties as antibiotics, antifungals, antivirals, anticoagulants, as well as their use as therapeutics, either alone or conjugated as glycoproteins.

Glycans in Medicinal Chemistry

The molecular recognition features of LSECtin toward asymmetric N-glycans have been scrutinized by NMR and compared to those occurring in glycan microarrays. A pair of positional glycan isomers (LDN3 and LDN6), a nonelongated GlcNAc4Man3 N-glycan (G0), and the minimum binding epitope (the GlcNAcβ1-2Man disaccharide) have been used to shed light on the preferred binding modes under both experimental conditions. Strikingly, both asymmetric LDN3 and LDN6 N-glycans are recognized by LSECtin with similar affinities in solution, in sharp contrast to the results obtained when those glycans are presented on microarrays, where only LDN6 was efficiently recognized by the lectin. Thus, different results can be obtained using different experimental approaches, pointing out the tremendous difficulty of translating in vitro results to the in vivo environment.

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.2c00719

Jesús Jiménez-Barbero

Papers

Chemical characterization of eucalypt pulp lignin during totally chlorine free bleaching including a laccase-mediator stage: 2D-NMR, FTIR and Py-GC/MS of enzymatically-isolated residual lignins.

Oral treatment with iododiflunisal delays beta amyloid plaque formation in a transgenic mouse model of Alzheimer Disease: a Longitudinal in vivo molecular imaging study

Corrigendum: Carbohydrate–Protein Interactions: A 3D View by NMR

Glycans in Medicinal Chemistry

Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition by LSECtin