J
Jesús Jiménez-Barbero
Researcher at Ikerbasque
Publications - 701
Citations - 21186
Jesús Jiménez-Barbero is an academic researcher from Ikerbasque. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Molecular recognition. The author has an hindex of 67, co-authored 673 publications receiving 18902 citations. Previous affiliations of Jesús Jiménez-Barbero include SIDI & Hunter College.
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Conformational studies on β-galactopyranosyl-(1->3) and (1->4)-xylopyranosides by NMR, molecular mechanics, molecular dynamics, and semiempirical
TL;DR: In this paper, the conformation of methyl 4-O-(β-D-galactopyranosyl)-β- D-xylopyranoide (1) and benzyl 3-O(β-d-galacticopyranosi) was investigated.
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RCM as a tool to freeze conformation of monosaccharides : synthesis of a β-mannopyranoside mimic adopting a conformation close to the biologically relevant B2,5 boat
Luis Amorim,Luis Amorim,Dolores Díaz,Luis P. Calle-Jiménez,Jesús Jiménez-Barbero,Pierre Sinaÿ,Pierre Sinaÿ,Yves Blériot,Yves Blériot +8 more
TL;DR: In this article, the synthesis of a β- d -mannopyranoside analog, which is fully identical to the naturally occurring d -mannose in terms of hydroxyl pattern, and displaying a skew boat conformation close to a B2,5 boat strongly believed to be adopted by the oxycarbenium transition state during glycosidic bond cleavage of β-mannane by family 26 βmannanase, is described.
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Structure of the Functional Domain of φ29 Replication Organizer INSIGHTS INTO OLIGOMERIZATION AND DNA BINDING
Juan Luis Asensio,Armando Albert,Daniel Muñoz-Espín,Carlos González,José Miguel Hermoso,Laurentino Villar,Jesús Jiménez-Barbero,Margarita Salas,Wilfried J. J. Meijer +8 more
TL;DR: A combination of NMR and x-ray approaches, combined with functional analyses of mutants, revealed that multimerization of p16.7C dimers is mediated by a large protein surface that is characterized by a striking self-complementarity, providing important clues about how protein multimerized and DNA binding are coupled.
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Conformational insights on the molecular recognition processes of carbohydrate molecules by proteins and enzymes: A 3D view by using NMR
Jesús Jiménez-Barbero,Juan Luis Asensio,Gabriel Cuevas,Ángeles Canales,María del Carmen Fernández-Alonso,F. Javier Cañada +5 more
TL;DR: In this paper, the essential structural and conformational features of protein-carbohydrate interactions and some applications of NMR spectroscopy to deal with this topic from different levels of complexity are discussed.
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Involvement of the glucose moiety in the molecular recognition of methyl β-lactoside by ricin: synthesis, conformational analysis, and binding studies of different derivatives at the C-3 region.
Paloma Fernández,Jesús Jiménez-Barbero,Manuel Martín-Lomas,Dolores Solís,Teresa Díaz-Mauriño +4 more
TL;DR: The binding of the different compounds to ricin, the galactose-specific toxin from Ricinus communis, has been investigated and the results confirm the involvement of the C-3 region in a nonpolar interaction with the protein at the periphery of the combining site.