Jia Yu

TL;DR: Older patients (>70 years) with comorbidities had a steeply increased risk of death with COVID-19 and Elevated high sensitivity troponin, neutrophils and depressed oxygen saturation predicted the rapid death of patients.

TL;DR: Inhibition of TLR4 signaling by TAK-242 alleviated oxidative stress and decreased inflammatory reaction and necroptosis, exerting a protective effect during AP in HFD rats, suggest that HFD exacerbated the extent and severity of AP.

TL;DR: Results proved that hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced acute pancreatitis, presumably because of its detoxification activity against excessive ROS, and inhibits the activation of NF-κB by affecting IκB nitration and degradation.

TL;DR: The results suggested that apocynin may attenuate intestinal barrier dysfunction in sodium taurocholate-induced SAP, presumably via its role in the prevention of reactive oxygen species generation and inhibition of p38 MAPK and NF-κB pathway activation.

TL;DR: The results suggest that PARP activation may contribute to kidney injury and thatPARP inhibitors may be beneficial in renal disorders associated with severe acute pancreatitis.