J
Jian-Bing Fan
Researcher at Affymetrix
Publications - 11
Citations - 4905
Jian-Bing Fan is an academic researcher from Affymetrix. The author has contributed to research in topics: SNP genotyping & Single-nucleotide polymorphism. The author has an hindex of 9, co-authored 11 publications receiving 4847 citations. Previous affiliations of Jian-Bing Fan include Massachusetts Institute of Technology.
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Journal ArticleDOI
Large-Scale Identification, Mapping, and Genotyping of Single-Nucleotide Polymorphisms in the Human Genome
David G. Wang,Jian-Bing Fan,Jian-Bing Fan,Chia-Jen Siao,Chia-Jen Siao,Anthony Berno,Anthony Berno,Peter M. Young,Peter M. Young,Ron Sapolsky,Ron Sapolsky,Ghassan Ghandour,Ghassan Ghandour,Nancy Perkins,Nancy Perkins,Ellen Winchester,Ellen Winchester,Jessica B. Spencer,Jessica B. Spencer,Leonid Kruglyak,Leonid Kruglyak,Lincoln Stein,Lincoln Stein,Linda Hsie,Linda Hsie,Thodoros Topaloglou,Thodoros Topaloglou,Earl Hubbell,Earl Hubbell,Elizabeth M. Robinson,Elizabeth M. Robinson,Michael P. Mittmann,Michael P. Mittmann,Macdonald S. Morris,Macdonald S. Morris,Naiping Shen,Naiping Shen,Dan Kilburn,Dan Kilburn,John D. Rioux,John D. Rioux,Chad Nusbaum,Chad Nusbaum,Steve Rozen,Steve Rozen,Thomas J. Hudson,Thomas J. Hudson,Robert J. Lipshutz,Robert J. Lipshutz,Mark S. Chee,Mark S. Chee,Eric S. Lander,Eric S. Lander +52 more
TL;DR: A large-scale survey for SNPs was examined by a combination of gel-based sequencing and high-density variation-detection DNA chips, and a genetic map was constructed showing the location of 2227 candidate SNPs.
Journal ArticleDOI
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
Marc K. Halushka,Jian-Bing Fan,Kimberly Bentley,Linda Hsie,Naiping Shen,Alan B. Weder,Richard S. Cooper,Robert J. Lipshutz,Aravinda Chakravarti +8 more
TL;DR: The degree of nucleotide polymorphism across these human genes, and orthologous great ape sequences, is highly variable and is correlated with the effects of functional conservation on gene sequences.
Journal ArticleDOI
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse.
Kerstin Lindblad-Toh,Ellen Winchester,Mark J. Daly,David G. Wang,David G. Wang,Joel N. Hirschhorn,Joel N. Hirschhorn,Jean-Philippe Laviolette,Kristin G. Ardlie,David Reich,Elizabeth M. Robinson,Pamela Sklar,Pamela Sklar,Nila Shah,Daryl J. Thomas,Jian-Bing Fan,Thomas R. Gingeras,Janet A. Warrington,Nila Patil,Thomas J. Hudson,Thomas J. Hudson,Eric S. Lander +21 more
TL;DR: A large-scale analysis of SNPs in the mouse genome and identifies a collection of 2,848 SNPs located in 1,755 sequence-tagged sites (STSs) using high-density oligonucleotide arrays, providing a first-generation SNP map of the mouse.
Journal ArticleDOI
Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays
Joseph G. Hacia,Jian-Bing Fan,Oliver A. Ryder,Li Jin,Li Jin,Keith Edgemon,G. Ghandour,R. A. Mayer,Bryan K. Sun,Linda Hsie,Christiane M. Robbins,Lawrence C. Brody,David G. Wang,Eric S. Lander,Robert J. Lipshutz,Stephen P. A. Fodor,Frank H. Collins +16 more
TL;DR: In a diverse human population set, it was found that SNP alleles with higher frequencies were more likely to be ancestral than less frequently occurring alleles.
Journal ArticleDOI
Parallel Genotyping of Human SNPs Using Generic High-density Oligonucleotide Tag Arrays
Jian-Bing Fan,Xiaoqiong Chen,Marc K. Halushka,Anthony Berno,Xiaohua Huang,Thomas B. Ryder,Robert J. Lipshutz,David J. Lockhart,Aravinda Chakravarti +8 more
TL;DR: A highly parallel method for genotyping single nucleotide polymorphisms (SNPs) using generic high-density oligonucleotide arrays that contain thousands of preselected 20-mer oligon nucleotide tags, which can be used for allele-frequency estimation in pooled DNA samples.