https://digital.csic.es/bitstream/10261/134282/5/ADVANCED%20TARGETED.pdf

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy.

Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery

Advanced materials and processing for drug delivery: The past and the future

Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: Promises, progress and prospects

Magnetic nanoparticles have been widely investigated for their great potential as mediators of heat for localised hyperthermia therapy. Nanocarriers have also attracted increasing attention due to the possibility of delivering drugs at specific locations, therefore limiting systematic effects. The enhancement of the anti-cancer effect of chemotherapy with application of concurrent hyperthermia was noticed more than thirty years ago. However, combining magnetic nanoparticles with molecules of drugs in the same nanoformulation has only recently emerged as a promising tool for the application of hyperthermia with combined chemotherapy in the treatment of cancer. The main feature of this review is to present the recent advances in the development of multifunctional therapeutic nanosystems incorporating both magnetic nanoparticles and drugs, and their superior efficacy in treating cancer compared to either hyperthermia or chemotherapy as standalone therapies. The principle of magnetic fluid hyperthermia is also presented.

/pdf/magnetic-nanoparticle-based-therapeutic-agents-for-thermo-4rqsnoqluh.pdf

Magnetic nanoparticle-based therapeutic agents for thermo-chemotherapy treatment of cancer

https://repository.um.edu.mo/bitstream/10692/4536/1/Gong-2012-Polymeric-micelles-drug-delivery-sy.pdf

Polymeric micelles drug delivery system in oncology

In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in vivo. This article summarizes recent advances in in vitro and in vivo research on the anti-cancer effects and related mechanisms of some promising natural products. These natural products are also reviewed for their therapeutic potentials, including flavonoids (gambogic acid, curcumin, wogonin and silibinin), alkaloids (berberine), terpenes (artemisinin, β-elemene, oridonin, triptolide, and ursolic acid), quinones (shikonin and emodin) and saponins (ginsenoside Rg3), which are isolated from Chinese medicinal herbs. In particular, the discovery of the new use of artemisinin derivatives as excellent anti-cancer drugs is also reviewed.

/pdf/anti-cancer-natural-products-isolated-from-chinese-medicinal-94ciy845uj.pdf

Jian Gong

Papers

Polymeric micelles drug delivery system in oncology

Anti-cancer natural products isolated from chinese medicinal herbs

Fighting fire with fire: poisonous Chinese herbal medicine for cancer therapy.