J
Jie Yao
Researcher at Yale University
Publications - 11
Citations - 184
Jie Yao is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 3 publications receiving 146 citations. Previous affiliations of Jie Yao include Third Military Medical University.
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Journal ArticleDOI
Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis
Rituparna Das,Mi Sun Koo,Bae Hoon Kim,Shevin T. Jacob,Selvakumar Subbian,Jie Yao,Lin Leng,Rebecca Levy,Charles Murchison,William J. Burman,Christopher C. Moore,W. Michael Scheld,John R. David,Gilla Kaplan,John D. MacMicking,Richard Bucala +15 more
TL;DR: The role of macrophage migration inhibitory factor (MIF), a cytokine that is encoded in a functionally polymorphic locus in humans, in TB is examined and genetic low expressers of MIF to be enriched in a population of patients with HIV and disseminated TB.
Journal ArticleDOI
Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus
Jie Yao,Lin Leng,Maor Sauler,Weiling Fu,Junsong Zheng,Yi Zhang,Xin Du,Xiaoqing Yu,Patty J. Lee,Richard Bucala +9 more
TL;DR: It is found that ICBP90 is essential for Mif transcription from monocytes/macrophages, B and T lymphocytes, and synovial fibroblasts, and TLR-induced MIF transcription is regulated in an ICBP 90- and -794 CATT5-8 length-dependent manner.
Journal ArticleDOI
Role of Macrophage Migration Inhibitory Factor in Granulomatosis With Polyangiitis.
Antoine G. Sreih,Rana Ezzedine,Lin Leng,Juan Fan,Jie Yao,Duncan Reid,Marta Piecychna,Simon Carette,David Cuthbertson,Paul F. Dellaripa,Gary S. Hoffman,Nader Khalidi,Curry L. Koening,Carol A. Langford,Alfred Mahr,Carol A. McAlear,Kathleen Maksimowicz-McKinnon,Paul A. Monach,Philip Seo,Ulrich Specks,E. William St. Clair,John H. Stone,Steven R. Ytterberg,Jeffrey C. Edberg,Peter A. Merkel,Richard Bucala +25 more
TL;DR: To examine the association between macrophage migration inhibitory factor promoter polymorphisms and granulomatosis with polyangiitis (GPA) in human subjects, and to assess the role of MIF in a murine model of granulOMatous vasculitis.
Journal ArticleDOI
Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma
Jie Yao,Shuming Tang,Chenyan Shi,Yunzhi Lin,Lanlan Ge,Qin-Hua Chen,Baoru Ou,Dongyu Liu,Yuyang Miao,Qiujie Xie,Xudong Tang,Jianwei Fei,Guang-Wei Yang,Jun Tian,Xiaobin Zeng +14 more
TL;DR: In this article , Isoginkgetin (ISO) exhibited cytotoxic activity against several types of cancer cells and its effects on hepatocellular carcinoma (HCC) cells and mechanism remain unclear.
Journal ArticleDOI
Prognostic value of Holliday junction-recognizing protein and its correlation with immune infiltrates in lung adenocarcinoma.
TL;DR: HJURP may be a potentially useful prognostic molecular biomarker of a poor prognosis in LUAD cases andGene set enrichment analysis results showed that genes involved with 'basal transcription factors', the 'cell cycle', 'homologous recombination', 'non-small cell lung cancer' (NSCLC), 'oocyte meiosis', 'p53 signaling pathway', 'pathways in cancer', 'RNA degradation' and 'spliceosome' were differentially enriched in