J
Jie-Yun Cai
Researcher at Chinese Academy of Sciences
Publications - 18
Citations - 461
Jie-Yun Cai is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Phenanthridine & Aphanamixis polystachya. The author has an hindex of 9, co-authored 17 publications receiving 368 citations.
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Journal ArticleDOI
Thermally robust Mo/CoFeB/MgO trilayers with strong perpendicular magnetic anisotropy
TL;DR: By replacing the Ta buffer layer with a thin Mo film, the PMA in the Ta/CoFeB/MgO structure is increased by 20%, and the thermal stability of the perpendicularly magnetized (001)Co FeB/ MgO films is greatly increased from 300°C to 425°C, making the Mo/Co Fe B/M gO films attractive for a practical p-MTJ application.
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Aphanamixoid A, a Potent Defensive Limonoid, with a New Carbon Skeleton from Aphanamixis polystachya
Jie-Yun Cai,Yu Zhang,Shi-Hong Luo,Duo-Zhi Chen,Gui-Hua Tang,Chun-Mao Yuan,Ying-Tong Di,Sheng-Hong Li,Xiao-Jiang Hao,Hongping He +9 more
TL;DR: The significant antifeedant activity of 1 against the generalist plant-feeding insect Helicoverpa armigera suggested it may be a potent defensive component of A. polystachya.
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Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition
Duo-Zhi Chen,Jie-Yun Cai,Junjun Cheng,Chen-xu Jing,Chen-xu Jing,Junlin Yin,Jian-Dong Jiang,Zong-Gen Peng,Xiao-Jiang Hao +8 more
TL;DR: Structural-activity analysis of a novel series of lycorine derivatives revealed that disubstitution on the free hydroxyl groups at C1 and C2 and/or degradation of the benzodioxole group would markedly reduce the cytotoxicity.
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Limonoids from Aphanamixis polystachya and their antifeedant activity.
Jie-Yun Cai,Duo-Zhi Chen,Shi-Hong Luo,Ning-Chuan Kong,Yu Zhang,Ying-Tong Di,Qiang Zhang,Juan Hua,Shu-Xi Jing,Shun-Lin Li,Sheng-Hong Li,Xiao-Jiang Hao,Hong-Ping He +12 more
TL;DR: On the basis of a preliminary structure-activity relationship analysis, some potential active sites in the aphanamixoid-type limonoid molecules are proposed.
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Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/β-Catenin Signaling Pathway Agonists.
Duo-Zhi Chen,Chen-xu Jing,Jie-Yun Cai,Ji-Bo Wu,Sheng Wang,Jun Lin Yin,Xiao-Nian Li,Lin Li,Xiao-Jiang Hao +8 more
TL;DR: Analysis of the structure-activity relationships of lycorine-derived phenanthridine derivatives as agonists of the Wnt/β-catenin signaling pathway and the results indicated that the combination of a 4-ethyldihydrophenanthridines skeleton and a triazole substituent improves Wnt activation suggests that triazoles groups are important pharmacophores for Wntactivation.