C
Chun-Mao Yuan
Researcher at Chinese Academy of Sciences
Publications - 103
Citations - 1228
Chun-Mao Yuan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 18, co-authored 74 publications receiving 890 citations. Previous affiliations of Chun-Mao Yuan include Shenyang Pharmaceutical University.
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Journal ArticleDOI
Aphanamixoid A, a Potent Defensive Limonoid, with a New Carbon Skeleton from Aphanamixis polystachya
Jie-Yun Cai,Yu Zhang,Shi-Hong Luo,Duo-Zhi Chen,Gui-Hua Tang,Chun-Mao Yuan,Ying-Tong Di,Sheng-Hong Li,Xiao-Jiang Hao,Hongping He +9 more
TL;DR: The significant antifeedant activity of 1 against the generalist plant-feeding insect Helicoverpa armigera suggested it may be a potent defensive component of A. polystachya.
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Peganumine A, a β-carboline dimer with a new octacyclic scaffold from Peganum harmala.
Kai-Bo Wang,Ying-Tong Di,Yu Bao,Chun-Mao Yuan,Gang Chen,Dahong Li,Jiao Bai,Hongping He,Xiao-Jiang Hao,Yue-Hu Pei,Yongkui Jing,Zhan-Lin Li,Hui-Ming Hua +12 more
TL;DR: Peganumine A, a new dimeric β-carboline alkaloid characterized by a unique 3,9-diazatetracyclo[6.5.2.0(1,9).0(3,8)]pentadec-2-one scaffold, was isolated from the seeds of Peganum harmala and showed moderate cytotoxic activity and selective effects on HL-60 cells with an IC50 value of 5.8 μM.
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Isolation and Asymmetric Total Synthesis of Perforanoid A.
Chao Lv,Xiao-Hui Yan,Qian Tu,Ying-Tong Di,Chun-Mao Yuan,Xin Fang,Yaacove Ben-David,Lei Xia,Jianxian Gong,Yuemao Shen,Zhen Yang,Xiao-Jiang Hao +11 more
TL;DR: Preliminary studies show that perforanoid A is cytotoxic towards HEL, K562, and CB3 tumor cell lines.
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Two Unusual Polycyclic Polyprenylated Acylphloroglucinols, Including a Pair of Enantiomers from Garcinia multiflora.
Yi-Min Fan,Ping Yi,Yang Li,Chen Yan,Tao Huang,Wei Gu,Yuan Ma,Lie-Jun Huang,Jian-Xin Zhang,Chonglin Yang,Yan Li,Chun-Mao Yuan,Xiao-Jiang Hao +12 more
TL;DR: Two polycyclic polyprenylated acylphloroglucinols, garcimulins A and B, including a pair of enantiomers with the unique caged tetracyclo skeleton were isolated from Garcinia multiflora and exhibited cytotoxic activities against five human cancer cell lines in vitro.
Journal ArticleDOI
Daphmacromines A-J, alkaloids from Daphniphyllum macropodum.
Ming-Ming Cao,Lei Wang,Yu Zhang,Hongping He,Yu-Cheng Gu,Qiang Zhang,Yan Li,Chun-Mao Yuan,Shun-Lin Li,Ying-Tong Di,Xiao-Jiang Hao +10 more
TL;DR: Five new yuzurimine-type Daphniphyllum alkaloids, daphmacromines K-O (1-5) showed moderate cytotoxic activity against brine shrimp and their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry.