J
Jimann Shin
Researcher at University of Washington
Publications - 34
Citations - 3279
Jimann Shin is an academic researcher from University of Washington. The author has contributed to research in topics: Zebrafish & Medicine. The author has an hindex of 20, co-authored 28 publications receiving 2948 citations. Previous affiliations of Jimann Shin include Harvard University & Vanderbilt University.
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Formation of the digestive system in zebrafish: III
Annie N. Y. Ng,Tanya A. de Jong Curtain,David J. Mawdsley,Sara J. White,Jimann Shin,Bruce Appel,P. Duc Si Dong,Didier Y.R. Stainier,Joan K. Heath +8 more
TL;DR: In this article, the morphological events that shape the zebrafish intestinal epithelium were investigated. But the authors focused on the period between 26 and 126 h post-fertilization (hpf) and followed the growth, lumen formation and differentiation of a continuous layer of endoderm into a functional intestinal epithelial with three morphologically distinct segments: the intestinal bulb, mid-intestine and posterior intestine.
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Analysis of Upstream Elements in the HuC Promoter Leads to the Establishment of Transgenic Zebrafish with Fluorescent Neurons
Hae Chul Park,Cheol-Hee Kim,Young Ki Bae,Sang-Yeob Yeo,Seok-Hyung Kim,Sung Kook Hong,Jimann Shin,Kyeong Won Yoo,Masahiko Hibi,Toshio Hirano,Naomasa Miki,Ajay B. Chitnis,Tae Lin Huh +12 more
TL;DR: Identification of key components of the HuC promoter has led to the establishment of a stable zebrafish transgenic line (HuC-GFP) in which GFP is expressed specifically in neurons.
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In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development
Brandon B Kirby,Norio Takada,Andrew J. Latimer,Jimann Shin,Thomas J. Carney,Thomas J. Carney,Robert N. Kelsh,Bruce Appel +7 more
TL;DR: In vivo time-lapse confocal microscopy is used to show that zebrafish OPCs continuously extend and retract numerous filopodium-like processes as they migrate and settle into their final positions, facilitating uniform spacing of oligodendrocytes and complete myelination.
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Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis
Annie N. Y. Ng,Tanya A. de Jong-Curtain,David J. Mawdsley,Sara J. White,Jimann Shin,Bruce Appel,P. Duc Si Dong,Didier Y.R. Stainier,Joan K. Heath +8 more
TL;DR: This analysis encompasses the period between 26 and 126 h post-fertilization and follows the growth, lumen formation and differentiation of a continuous layer of endoderm into a functional intestinal epithelium with three morphologically distinct segments: the intestinal bulb, mid-intestine and posterior intestine.
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Activated ALK Collaborates with MYCN in Neuroblastoma Pathogenesis
Shizhen Zhu,Jeong-Soo Lee,Feng Guo,Jimann Shin,Antonio R. Perez-Atayde,Jeffery L. Kutok,Scott J. Rodig,Donna Neuberg,Daniel Helman,Hui Feng,Rodney A. Stewart,Wenchao Wang,Rani E. George,Rani E. George,John P. Kanki,A. Thomas Look,A. Thomas Look +16 more
TL;DR: A transgenic zebrafish model of neuroblastoma is generated in which MYCN-induced tumors arise from a subpopulation of neuroblasts that migrate into the adrenal medulla analog following organogenesis, and coexpression of activated ALK with MYCN in this model triples the disease penetrance and markedly accelerates tumor onset.