J
Jimena Salido
Researcher at University of Buenos Aires
Publications - 12
Citations - 178
Jimena Salido is an academic researcher from University of Buenos Aires. The author has contributed to research in topics: Immune system & Viral load. The author has an hindex of 6, co-authored 11 publications receiving 106 citations. Previous affiliations of Jimena Salido include National Scientific and Technical Research Council.
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Journal ArticleDOI
Induction of HIF-1α by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation.
Gabriel Duette,Pehuén Pereyra Gerber,Julia Rubione,Paula Soledad Pérez,Alan L. Landay,Suzanne M. Crowe,Suzanne M. Crowe,Suzanne M. Crowe,Zhaohao Liao,Kenneth W. Witwer,María Pía Holgado,Jimena Salido,Jorge Geffner,Omar Sued,Clovis S. Palmer,Clovis S. Palmer,Clovis S. Palmer,Matias Ostrowski +17 more
TL;DR: This study demonstrates that HIF-1α plays a crucial role in HIV-1 pathogenesis by promoting viral replication and the release of EVs that orchestrate lymphocyte- and macrophage-mediated inflammatory responses.
Journal ArticleDOI
Low Proviral Load is Associated with Indeterminate Western Blot Patterns in Human T-Cell Lymphotropic Virus Type 1 Infected Individuals: Could Punctual Mutations be Related?
Camila Cánepa,Jimena Salido,Matías Ruggieri,Sindy Fraile,Gabriela Pataccini,Carolina Berini,Mirna Biglione +6 more
TL;DR: Indeterminate WB results confirmed later as HTLV-1 positive may be associated with low PVL levels, and mutations in LTR and tax are described; their functional relevance remains to be determined.
Journal ArticleDOI
Impact of HIV-ART on the restoration of Th17 and Treg cells in blood and female genital mucosa.
María Paula Caruso,Juliana Falivene,María Pía Holgado,Diego Hernán Zurita,Natalia Laufer,Carina Castro,Ángeles Nico,Cynthia Maeto,Jimena Salido,Héctor Rodríguez Pérez,Horacio Salomón,Pedro Cahn,Omar Sued,Valeria Fink,Gabriela Turk,María Magdalena Gherardi +15 more
TL;DR: Antiretroviral treatment did not restore Th17-related immune functions completely at the female mucosal level, and positive correlations between these cells and the levels of IL-17F and IL-21 production by CMCs may suggest that a better homing of These cells to the intestine could also imply a better restoration of these cells in the female genital tract.
Journal ArticleDOI
PD-1 Expression in HIV-Specific CD8+ T cells Before Antiretroviral Therapy Is Associated With HIV Persistence.
Yanina Alexandra Ghiglione,César Ariel Trifone,Jimena Salido,Ajantha Rhodes,María Julia Ruiz,María Laura Polo,Horacio Salomón,Natalia Laufer,Omar Sued,Sharon R Lewin,Gabriela Turk +10 more
TL;DR: The quality of the early CD8+ T-cell immune response may serve as a predictor of HIV persistence on ART after treatment of primary infection.
Journal ArticleDOI
Phenotype, Polyfunctionality, and Antiviral Activity of in vitro Stimulated CD8+ T-Cells From HIV+ Subjects Who Initiated cART at Different Time-Points After Acute Infection.
Jimena Salido,María Julia Ruiz,César Ariel Trifone,María Inés Figueroa,María Paula Caruso,María Magdalena Gherardi,Omar Sued,Horacio Salomón,Natalia Laufer,Yanina Alexandra Ghiglione,Gabriela Turk +10 more
TL;DR: It is shown that, despite being dampened in subjects on cART, the HIV-specific CD8TC response could be selectively stimulated and expanded in vitro, presenting a high proportion of cells able to carry-out multiple effector functions.