J
Jimmy K. Eng
Researcher at University of Washington
Publications - 171
Citations - 37832
Jimmy K. Eng is an academic researcher from University of Washington. The author has contributed to research in topics: Mass spectrometry & Proteome. The author has an hindex of 77, co-authored 168 publications receiving 35701 citations. Previous affiliations of Jimmy K. Eng include Oregon Health & Science University & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues.
Sun-Il Hwang,Jaykumar Thumar,Deborah H. Lundgren,Karim Rezaul,Viveka Mayya,Linfeng Wu,Jimmy K. Eng,Michael E. Wright,David K. Han +8 more
TL;DR: Direct tissue proteomics (DTP) is developed, which can be used to identify proteins directly from formalin-fixed paraffin-embedded prostate cancer tissue samples and validated Wnt-3 as an upregulated protein in cancerous prostate cells by immunohistochemistry.
Journal ArticleDOI
Human Plasma PeptideAtlas
Eric W. Deutsch,Jimmy K. Eng,Hui Zhang,Nichole L. King,Alexey I. Nesvizhskii,Biaoyang Lin,Hookeun Lee,Eugene C. Yi,Reto Ossola,Ruedi Aebersold,Ruedi Aebersold +10 more
TL;DR: The resulting compendium of peptides and their associated samples, proteins, and genes is made publicly available as a reference for future research on human plasma.
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Identification of 2D-gel proteins: A comparison of MALDI/TOF peptide mass mapping to μ LC-ESI tandem mass spectrometry
Hanjo Lim,Jimmy K. Eng,John R. Yates,Sandra L. Tollaksen,Carol S. Giometti,James F. Holden,Michael W. W. Adams,Claudia I. Reich,Gary J. Olsen,Lara G. Hays +9 more
TL;DR: Improved sequence coverage in combination with enzymatic digestions of different specificity is proposed as a method for analysis of post-translational modification from 2D-gel separated proteins.
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Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry.
Sabine P. Schrimpf,Virginia Meskenaite,Erich Brunner,Dorothea Rutishauser,Dorothea Rutishauser,Pascal Walther,Jimmy K. Eng,Ruedi Aebersold,Peter Sonderegger +8 more
TL;DR: An inventory of the synaptic proteome is provided and the suitability of the ICAT method for the assessment of synaptic structure, function and plasticity is confirmed.
Journal ArticleDOI
A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry.
Sheng Pan,Sheng Pan,David Zhu,Joseph F. Quinn,Elaine R. Peskind,Thomas J. Montine,Biaoyang Lin,David R. Goodlett,Greg K. Taylor,Jimmy K. Eng,Jing Zhang +10 more
TL;DR: This report summarizes the efforts to comprehensively characterize the human CSF proteome to date by utilizing several different separation methodologies and mass spectrometric platforms that greatly enhanced the identification coverage and the depth of protein profiling of CSF to characterize CSFroteome.