David Zhu

TL;DR: The preliminary findings of iTRAQ suggest that a roster of proteins may be generated and developed into specific biomarkers that could eventually assist in clinical diagnosis and monitoring disease progression of AD, PD and DLB.

TL;DR: This investigation represents the first extensive proteomic investigation of corticalLBs, and it is expected that characterization of the proteins in the cortical LBs may reveal novel mechanisms by which LB forms and pathways leading to neurodegeneration in DLB and/or advanced PD.

TL;DR: The magnetization-prepared RAGE sequence, as compared with the fast spin-echo and TOF sequences, demonstrated higher diagnostic capability for the detection and quantification of IPH.

TL;DR: It is confirmed that there was no direct interaction between α-synuclein and DJ-1 but also, for the first time, report these five novel proteins to be associating with both α- synucleIn andDJ-1.

TL;DR: This report summarizes the efforts to comprehensively characterize the human CSF proteome to date by utilizing several different separation methodologies and mass spectrometric platforms that greatly enhanced the identification coverage and the depth of protein profiling of CSF to characterize CSFroteome.