Jimmy K. Eng

TL;DR: The identity of few bacterial cells present in unknown samples can be easily, rapidly and accurately established by adopting a procedure involving simple sample processing followed by direct mass spectral analysis and data processing.

TL;DR: Mango is an open source software tool that extracts precursor masses from chimeric spectra generated using cleavable cross-linkers that provides an avenue to perform whole proteome cross-linking experiments without specialized instrumentation or access to nonstandard methods.

TL;DR: It is shown that PLRV virions have hot spots of protein interaction and multifunctional surface topologies, revealing how these plant viruses maximize their use of binding interfaces and demonstrating the usefulness of PIR technology for precision mapping of functional host-pathogen protein interaction topologies.

TL;DR: A set of specific and quantitative targeted mass spectrometry assays are developed to determine the frequency of different types of inter-ubiquitin linkages in poly-ubsitin chains relative to the total ubiquitin concentration.

TL;DR: This work has created the largest database to date of high-confidence sequence assignments to characterize the appearance of immonium ions in CID spectra using a QTOF instrument under "typical" operating conditions and clearly demonstrated a positional effect whereby the proximity of the amino acid generating theImmonium ion to the amino terminal of the peptide correlates with the strength of the immonia ion peak.