J
Jin Yuan
Researcher at Cell Signaling Technology
Publications - 2
Citations - 2467
Jin Yuan is an academic researcher from Cell Signaling Technology. The author has contributed to research in topics: Receptor tyrosine kinase & Tyrosine kinase. The author has an hindex of 2, co-authored 2 publications receiving 2309 citations.
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Journal ArticleDOI
Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer
Klarisa Rikova,Ailan Guo,Qingfu Zeng,Anthony Possemato,Jian Yu,Herbert Haack,Julie Nardone,Kimberly Lee,Cynthia Reeves,Yu Li,Yerong Hu,Zhi-Ping Tan,Matthew P. Stokes,Laura Sullivan,Jeffrey Mitchell,Randy Wetzel,Joan MacNeill,Jian Min Ren,Jin Yuan,Corey E. Bakalarski,Judit Villén,Jon M. Kornhauser,Bradley L. Smith,Daiqiang Li,Xinmin Zhou,Steven P. Gygi,Ting-Lei Gu,Roberto D. Polakiewicz,John Rush,Michael J. Comb +29 more
TL;DR: By focusing on activated cell circuitry, the approach outlined here provides insight into cancer biology not available at the chromosomal and transcriptional levels and can be applied broadly across all human cancers.
Journal ArticleDOI
Survey of Tyrosine Kinase Signaling Reveals ROS Kinase Fusions in Human Cholangiocarcinoma
Ting-Lei Gu,Xiaxing Deng,Feizhou Huang,Meghan Ann Tucker,Katherine Crosby,Victoria Rimkunas,Yi Wang,Gang Deng,Lei Zhu,Zhi-Ping Tan,Yerong Hu,Chun-Lin Wu,Julie Nardone,Joan MacNeill,Jianmin Ren,Cynthia Reeves,Gregory Innocenti,Brett Norris,Jin Yuan,Jian Yu,Herbert Haack,Baiyong Shen,Chenghong Peng,Hongwei Li,Xinmin Zhou,Xunyang Liu,John Rush,Michael J. Comb +27 more
TL;DR: It is demonstrated that ROS kinase is a promising candidate for a therapeutic target and for a diagnostic molecular marker in cholangiocarcinoma and suggests that a more broadly based screen for activated ROS kinases in cancer is warranted.