J
Jing Q. Lan
Publications - 4
Citations - 1625
Jing Q. Lan is an academic researcher. The author has contributed to research in topics: Epileptogenesis & Adenosine A1 receptor. The author has an hindex of 4, co-authored 4 publications receiving 1564 citations.
Papers
More filters
Journal ArticleDOI
Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
Kunlin Jin,Manabu Minami,Jing Q. Lan,Xiao Ou Mao,Sophie Batteur,Roger P. Simon,David A. Greenberg +6 more
TL;DR: A role for ischemia-induced neurogenesis in what may be adaptive processes that contribute to recovery after stroke is supported.
Journal ArticleDOI
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice
Tianfu Li,Gaoying Ren,Theresa A. Lusardi,Andrew Wilz,Jing Q. Lan,Takuji Iwasato,Shigeyoshi Itohara,Roger P. Simon,Detlev Boison +8 more
TL;DR: It is demonstrated that upregulation of ADK and spontaneous focal electroencephalographic seizures were both restricted to the affected CA3, and suggested that astrocyte-based ADK provides a critical link between astrogliosis and neuronal dysfunction in epilepsy.
Journal ArticleDOI
Adenosine A1 receptors are crucial in keeping an epileptic focus localized.
TL;DR: It is concluded that activation of A1 receptors by ambient adenosine is crucial in keeping epileptic foci localized and further demonstrate its importance in preventing the progression of status epilepticus to lethal consequences.
Journal ArticleDOI
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants
Tianfu Li,Julius A. Steinbeck,Theresa Lusardi,Philipp Koch,Jing Q. Lan,Andrew Wilz,Michaela Segschneider,Roger P. Simon,Oliver Brüstle,Detlev Boison +9 more
TL;DR: It is concluded that ES cell-derived adenosine releasing brain implants are superior to paracrineadenosine release from BHK-AK2 cell implants in suppressing seizure progression in the rat kindling-model, which may indicate a potential antiepileptogenic function of stem cell-mediatedAdenosine delivery.