J
Jinhua Wang
Researcher at Peking Union Medical College
Publications - 56
Citations - 2269
Jinhua Wang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 21, co-authored 53 publications receiving 1498 citations.
Papers
More filters
Journal ArticleDOI
FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer
Partha Ray,Jinhua Wang,Ying Qu,Myung-Shin Sim,Jaime Shamonki,Sanjay P. Bagaria,Xing Ye,Bingya Liu,David Elashoff,Dave S.B. Hoon,Michael A. Walter,John W.M. Martens,Andrea L. Richardson,Armando E. Giuliano,Xiaojiang Cui +14 more
TL;DR: Findings identify FOXC1 as a theranostic biomarker that is specific for BLBC, offering not only a potential prognostic candidate but also a potential molecular therapeutic target in this breast cancer subtype.
Journal ArticleDOI
The biology, function, and applications of exosomes in cancer
Jinyi Liu,Liwen Ren,Sha Li,Wan Li,Xiangjin Zheng,Yihui Yang,Weiqi Fu,Jie Yi,Jinhua Wang,Guanhua Du +9 more
TL;DR: Exosomes in liquid biopsies can be used as non-invasive biomarkers for early detection and diagnosis of cancers.
Journal ArticleDOI
MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A
Katsuya Ohta,Hiromitsu Hoshino,Jinhua Wang,Shigeshi Ono,Yuuki Iida,Keisuke Hata,Sharon K. Huang,Steven D. Colquhoun,Dave S.B. Hoon +8 more
TL;DR: It is concluded that miR-93 stimulated cell proliferation, migration, and invasion through the oncogenic c-Met/PI3K/Akt pathway and also inhibited apoptosis by directly inhibiting PTEN and CDKN1A expression in human HCC.
Journal ArticleDOI
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling
Ying Qu,Jinhua Wang,Partha Ray,Hua Guo,Jian Huang,Miyung Shin-Sim,Bolanle A. Bukoye,Bingya Liu,Adrian V. Lee,Xin Lin,Peng Huang,John W.M. Martens,Armando E. Giuliano,Ning Zhang,Ning Hui Cheng,Xiaojiang Cui +15 more
TL;DR: It is demonstrated that the redox protein thioredoxin-like 2 (TXNL2) regulates the growth and metastasis of human breast cancer cells through a redox signaling mechanism and suggested that TXNL2 could be a target for treatment of breast cancer.
Journal ArticleDOI
B7-H3 associated with tumor progression and epigenetic regulatory activity in cutaneous melanoma.
Jinhua Wang,Kelly Chong,Yoshitaka Nakamura,Linhda Nguyen,Sharon K. Huang,Christine Kuo,Wang Zhang,Hua Yu,Donald L. Morton,Dave S.B. Hoon +9 more
TL;DR: It is demonstrated that melanoma B7-H3 expression was correlated to p-STAT3 activity level in melanoma tissues and cell lines and significantly associated with melanoma-specific survival in both stage III and stage IV melanoma patients.