J
Jinyu Zhu
Researcher at Zhejiang University
Publications - 9
Citations - 282
Jinyu Zhu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Colitis & Inflammatory bowel disease. The author has an hindex of 4, co-authored 9 publications receiving 46 citations.
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Journal ArticleDOI
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma
Bufu Tang,Jinyu Zhu,Jie Li,Kai Fan,Yang Gao,Yang Gao,Shimiao Cheng,Chunli Kong,Chunli Kong,Liyun Zheng,Fazong Wu,Fazong Wu,Qiaoyou Weng,Qiaoyou Weng,Chenying Lu,Chenying Lu,Jiansong Ji,Jiansong Ji +17 more
TL;DR: The prognostic and diagnostic models based on the four genes indicated superior diagnostic and predictive performance, indicating new possibilities for individualized treatment of HCC patients.
Journal ArticleDOI
Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis.
Bufu Tang,Jinyu Zhu,Shiji Fang,Yajie Wang,Rajamanickam Vinothkumar,Mengyao Li,Qiaoyou Weng,Liyun Zheng,Yang Yang,Rongfang Qiu,Min Xu,Zhongwei Zhao,Jiansong Ji +12 more
TL;DR: In this paper, the regulatory effect of OTSSP167 (a MELK-selective inhibitor) on the mice models of colitis and colitis-associated carcinogenesis was analyzed.
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Therapeutic Potential of Triptolide as an Anti-Inflammatory Agent in Dextran Sulfate Sodium-Induced Murine Experimental Colitis.
Bufu Tang,Jinyu Zhu,Baohui Zhang,Fazong Wu,Fazong Wu,Yajie Wang,Yajie Wang,Qiaoyou Weng,Shiji Fang,Liyun Zheng,Yang Yang,Yang Yang,Rongfang Qiu,Rongfang Qiu,Minjiang Chen,Minjiang Chen,Min Xu,Min Xu,Zhongwei Zhao,Zhongwei Zhao,Jiansong Ji,Jiansong Ji +21 more
TL;DR: Investigation of the anti-inflammatory effects of triptolide in a dextran sulfate sodium (DSS)-induced mouse colitis model and LPS-activated macrophages revealed PDE4B as a target molecule, thus providing new ideas for the treatment of IBD.
Journal ArticleDOI
Diagnosis and prognosis models for hepatocellular carcinoma patient’s management based on tumor mutation burden
Bufu Tang,Jinyu Zhu,Zhongwei Zhao,Zhongwei Zhao,Chenying Lu,Chenying Lu,Siyu Liu,Shiji Fang,Liyun Zheng,Nannan Zhang,Minjiang Chen,Minjiang Chen,Min Xu,Min Xu,Ri-Sheng Yu,Jiansong Ji,Jiansong Ji +16 more
TL;DR: This study identifies TMB-specific genes with good prognostic value to build diagnostic and prognostic models and provide guidance for the treatment of HCC patients and provides new ideas for developing treatment strategies to improve disease outcomes.
Journal ArticleDOI
Identification of critical ferroptosis regulators in lung adenocarcinoma that RRM2 facilitates tumor immune infiltration by inhibiting ferroptotic death.
Bufu Tang,Wangting Xu,Yajie Wang,Jinyu Zhu,Hailin Wang,Jianfei Tu,Qiaoyou Weng,Chunli Kong,Yang Yang,Rongfang Qiu,Zhongwei Zhao,Min Xu,Min Xu,Jiansong Ji,Jiansong Ji +14 more
TL;DR: In this paper, the authors defined ferroptosis regulators in lung adenocarcinoma (LUAD) patients through database analysis and experimental validation to determine the implementation of genes associated with clinical relevance, immunotherapy response and tumor microenvironment in LUAD patients.