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Bufu Tang
Researcher at Zhejiang University
Publications - 23
Citations - 447
Bufu Tang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 5, co-authored 11 publications receiving 67 citations.
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Journal ArticleDOI
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma
Bufu Tang,Jinyu Zhu,Jie Li,Kai Fan,Yang Gao,Yang Gao,Shimiao Cheng,Chunli Kong,Chunli Kong,Liyun Zheng,Fazong Wu,Fazong Wu,Qiaoyou Weng,Qiaoyou Weng,Chenying Lu,Chenying Lu,Jiansong Ji,Jiansong Ji +17 more
TL;DR: The prognostic and diagnostic models based on the four genes indicated superior diagnostic and predictive performance, indicating new possibilities for individualized treatment of HCC patients.
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Sialic acid-engineered mesoporous polydopamine nanoparticles loaded with SPIO and Fe3+ as a novel theranostic agent for T1/T2 dual-mode MRI-guided combined chemo-photothermal treatment of hepatic cancer
Gaofeng Shu,Minjiang Chen,Jingjing Song,Xiao-Ling Xu,Chenying Lu,Yuyin Du,Min Xu,Zhongwei Zhao,Minxia Zhu,Kai Fan,Xiaoxi Fan,Shiji Fang,Bufu Tang,Yiyang Dai,Yong-Zhong Du,Jiansong Ji +15 more
TL;DR: In vitro and in vivo studies revealed that SA-MPDA@SPIO/DOX/Fe3+ NPs could effectively target to the hepatic tumor tissue, which was possibly due to the specific interaction between SA and the overexpressed E-selectin.
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Pharmacological inhibition of MELK restricts ferroptosis and the inflammatory response in colitis and colitis-propelled carcinogenesis.
Bufu Tang,Jinyu Zhu,Shiji Fang,Yajie Wang,Rajamanickam Vinothkumar,Mengyao Li,Qiaoyou Weng,Liyun Zheng,Yang Yang,Rongfang Qiu,Min Xu,Zhongwei Zhao,Jiansong Ji +12 more
TL;DR: In this paper, the regulatory effect of OTSSP167 (a MELK-selective inhibitor) on the mice models of colitis and colitis-associated carcinogenesis was analyzed.
Journal ArticleDOI
Therapeutic Potential of Triptolide as an Anti-Inflammatory Agent in Dextran Sulfate Sodium-Induced Murine Experimental Colitis.
Bufu Tang,Jinyu Zhu,Baohui Zhang,Fazong Wu,Fazong Wu,Yajie Wang,Yajie Wang,Qiaoyou Weng,Shiji Fang,Liyun Zheng,Yang Yang,Yang Yang,Rongfang Qiu,Rongfang Qiu,Minjiang Chen,Minjiang Chen,Min Xu,Min Xu,Zhongwei Zhao,Zhongwei Zhao,Jiansong Ji,Jiansong Ji +21 more
TL;DR: Investigation of the anti-inflammatory effects of triptolide in a dextran sulfate sodium (DSS)-induced mouse colitis model and LPS-activated macrophages revealed PDE4B as a target molecule, thus providing new ideas for the treatment of IBD.
Journal ArticleDOI
Diagnosis and prognosis models for hepatocellular carcinoma patient’s management based on tumor mutation burden
Bufu Tang,Jinyu Zhu,Zhongwei Zhao,Zhongwei Zhao,Chenying Lu,Chenying Lu,Siyu Liu,Shiji Fang,Liyun Zheng,Nannan Zhang,Minjiang Chen,Minjiang Chen,Min Xu,Min Xu,Ri-Sheng Yu,Jiansong Ji,Jiansong Ji +16 more
TL;DR: This study identifies TMB-specific genes with good prognostic value to build diagnostic and prognostic models and provide guidance for the treatment of HCC patients and provides new ideas for developing treatment strategies to improve disease outcomes.