J
Joan Massagué
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 415
Citations - 160448
Joan Massagué is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Transforming growth factor beta & Transforming growth factor. The author has an hindex of 189, co-authored 408 publications receiving 149951 citations. Previous affiliations of Joan Massagué include Brown University & University of Barcelona.
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Journal ArticleDOI
TGF-beta signal transduction.
TL;DR: The transforming growth factor beta (TGF-beta) family of growth factors control the development and homeostasis of most tissues in metazoan organisms and mutations in these pathways are the cause of various forms of human cancer and developmental disorders.
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Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
Yigong Shi,Joan Massagué +1 more
TL;DR: Current understanding on the mechanisms of TGF-β signaling from cell membrane to the nucleus is presented and the transcriptional regulation of target gene expression is reviewed.
Journal ArticleDOI
Cancer Metastasis: Building a Framework
Gaorav P. Gupta,Joan Massagué +1 more
TL;DR: Understanding of the origins and nature of cancer metastasis and the selection of traits that are advantageous to cancer cells is promoted.
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TGFβ in Cancer
TL;DR: The mechanistic basis and clinical relevance of TGFbeta's role in cancer is becoming increasingly clear, paving the way for a better understanding of the complexity and therapeutic potential of this pathway.