John D. Bradley

TL;DR: The GAIT trial as discussed by the authors evaluated the efficacy and safety of glucosamine and chondroitin sulfate as a treatment for knee pain from osteoarthritis in 1583 patients.

TL;DR: In this article, the authors compared the efficacy of ibuprofen, given in either an antiinflammatory dose (high dose) or an analgesic dose (low dose), with that of acetaminophen, a pure analgesic.

TL;DR: In short-term, symptomatic treatment of osteoarthritis of the knee, the efficacy of acetaminophen was similar to that of ibuprofen, whether the latter was administered in an analgesic or an antiinflammatory dose.

TL;DR: This study surveyed a representative clinical sample of patients who were currently receiving allopathic care for rheumatologic conditions to determine the prevalence and types of CAM used, patients' perceptions about CAM's efficacy, reasons for using CAM, potential patient communication barriers about CAM use, and correlates of CAM use and discussion of CAM with a physician.

TL;DR: Doxycycline slowed the rate of joint space narrowing in knees with established OA, and its lack of effect on JSN in the contralateral knee suggests that pathogenetic mechanisms in that joint were different from those in the index knee.