J
John M. Quarles
Researcher at Texas A&M Health Science Center
Publications - 30
Citations - 1440
John M. Quarles is an academic researcher from Texas A&M Health Science Center. The author has contributed to research in topics: Vaccination & Virus. The author has an hindex of 20, co-authored 30 publications receiving 1334 citations. Previous affiliations of John M. Quarles include Texas A&M University System & Texas A&M University.
Papers
More filters
Journal ArticleDOI
Antibody Correlates and Predictors of Immunity to Naturally Occurring Influenza in Humans and the Importance of Antibody to the Neuraminidase
Robert B. Couch,Robert L. Atmar,Luis M. Franco,John M. Quarles,Janet M. Wells,Nancy Arden,Diane Niño,John W. Belmont +7 more
TL;DR: Increasing anti-HA and NA antibody in serum and secretions correlated with reducing pH1N1 influenza virus infection and illness in healthy young adults.
Journal ArticleDOI
Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans
Kristine L. Bucasas,Luis M. Franco,Chad A. Shaw,Molly S. Bray,Janet M. Wells,Diane Niño,Nancy Arden,John M. Quarles,Robert B. Couch,John W. Belmont +9 more
TL;DR: The results highlight the role of a systems biology approach in understanding the molecular events that take place in vivo after influenza vaccination and in the development of better predictors of vaccine responsiveness.
Journal ArticleDOI
Integrative genomic analysis of the human immune response to influenza vaccination
Luis M. Franco,Kristine L. Bucasas,Janet M. Wells,Diane Niño,Xueqing Wang,Gladys Zapata,Nancy Arden,Alexander Renwick,Peng Yu,John M. Quarles,Molly S. Bray,Robert B. Couch,John W. Belmont,Chad A. Shaw +13 more
TL;DR: An integrative, longitudinal study combining genetic, transcriptional, and immunologic data in humans given seasonal influenza vaccine shows that variation at the level of genes involved in membrane trafficking and antigen processing significantly influences the human response to influenza vaccination.
Journal ArticleDOI
Host Transcriptional Response to Influenza and Other Acute Respiratory Viral Infections--A Prospective Cohort Study.
Yijie Zhai,Luis M. Franco,Robert L. Atmar,John M. Quarles,Nancy Arden,Kristine L. Bucasas,Janet M. Wells,Diane Niño,Xueqing Wang,Gladys Zapata,Chad A. Shaw,John W. Belmont,Robert B. Couch +12 more
TL;DR: The results, which were replicated between two seasons, showed a dramatic upregulation of interferon pathway and innate immunity genes and induced a higher magnitude and longer duration of the shared expression signature of illness compared to the other viral infections.
Journal ArticleDOI
Sporadic occurrence of zoonotic swine influenza virus infections.
TL;DR: Two infections by swine influenza virus, antigenically similar to A/New Jersey/76 (H1N1) virus, were detected during community epidemics with other influenza viruses during virological surveillance of acute respiratory illnesses.