J
John P. Rossiter
Researcher at Queen's University
Publications - 38
Citations - 1924
John P. Rossiter is an academic researcher from Queen's University. The author has contributed to research in topics: Rabies virus & Encephalitis. The author has an hindex of 17, co-authored 37 publications receiving 1599 citations. Previous affiliations of John P. Rossiter include Kingston General Hospital.
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Journal ArticleDOI
Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma
James Perry,Normand Laperriere,Christopher J. O'Callaghan,Alba A. Brandes,Johan Menten,Claire Phillips,Michael Fay,Michael Fay,Ryo Nishikawa,J. Gregory Cairncross,Wilson Roa,David Osoba,John P. Rossiter,Arjun Sahgal,H Hirte,Florence Laigle-Donadey,Enrico Franceschi,Olivier Chinot,Vassilis Golfinopoulos,L. Fariselli,Antje Wick,Loïc Feuvret,Michael Back,Michael Tills,Chad Winch,Brigitta G. Baumert,Wolfgang Wick,Keyue Ding,Warren P. Mason +28 more
TL;DR: In elderly patients with glioblastoma, the addition of temozolomide to short‐course radiotherapy resulted in longer survival than short‐ Course radiotherapy alone.
Journal ArticleDOI
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study
Brigitta G. Baumert,Brigitta G. Baumert,Monika E. Hegi,Martin J. van den Bent,Andreas von Deimling,Thierry Gorlia,Khê Hoang-Xuan,Alba A. Brandes,Guy Kantor,Martin J.B. Taphoorn,Mohamed Ben Hassel,Christian Hartmann,Christian Hartmann,Gail Ryan,David Capper,Johan M. Kros,Sebastian Kurscheid,Sebastian Kurscheid,Wolfgang Wick,Roelien H. Enting,Michele Reni,Brian Thiessen,Frédéric Dhermain,Jacoline E C Bromberg,Loïc Feuvret,Jaap C. Reijneveld,Olivier Chinot,J.M.M. Gijtenbeek,John P. Rossiter,Nicolas Dif,Carmen Balana,Jose Bravo-Marques,Paul Clement,Christine Marosi,Tzahala Tzuk-Shina,Robert A Nordal,Jeremy Rees,Denis Lacombe,Warren P. Mason,Roger Stupp,Roger Stupp +40 more
TL;DR: There was no significant difference in outcome of the overall patient population treated with either radiotherapy alone or TMZ chemotherapy alone, and further data maturation is needed for overall survival analyses and evaluation of the full predictive impact of the molecular subtypes for individualized treatment choices.
Journal ArticleDOI
Apoptosis plays an important role in experimental rabies virus infection.
Alan Jackson,John P. Rossiter +1 more
TL;DR: Adult ICR mice inoculated intracerebrally with CVS showed morphologic changes of apoptosis, DNA fragmentation, and increased Bax expression in neurons, with changes most marked in the hippocampus and cerebral cortex.
Journal ArticleDOI
Structural Abnormalities in Neurons Are Sufficient To Explain the Clinical Disease and Fatal Outcome of Experimental Rabies in Yellow Fluorescent Protein-Expressing Transgenic Mice
TL;DR: In this paper, the effects of rabies virus infection on the structure of neurons were investigated with experimentally infected transgenic mice expressing yellow fluorescent protein (YFP) in neuronal subpopulations.
Journal ArticleDOI
Expression of Toll-like receptor 3 in the human cerebellar cortex in rabies, herpes simplex encephalitis, and other neurological diseases
TL;DR: This study has provided evidence that human brain neurons can express TLR-3 in vivo and suggests that neurons may play an important role in initiating an inflammatory reaction in a variety of neurological diseases.