J
Jaap C. Reijneveld
Researcher at VU University Medical Center
Publications - 153
Citations - 9793
Jaap C. Reijneveld is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Medicine & Temozolomide. The author has an hindex of 43, co-authored 131 publications receiving 7751 citations. Previous affiliations of Jaap C. Reijneveld include Academic Medical Center.
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Journal ArticleDOI
Graph theoretical analysis of complex networks in the brain
TL;DR: These studies suggest that the human brain can be modelled as a complex network, and may have a small-world structure both at the level of anatomical as well as functional connectivity, and increasing evidence that various types of brain disease may be associated with deviations of the functional network topology from the optimal small- world pattern.
Journal ArticleDOI
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics
Myron G. Best,Nik Sol,Irsan E. Kooi,Jihane Tannous,Bart A. Westerman,François Rustenburg,Pepijn Schellen,Heleen Verschueren,Edward Post,Jan Koster,Bauke Ylstra,Najim Ameziane,Josephine C. Dorsman,Egbert F. Smit,Henk M.W. Verheul,David P. Noske,Jaap C. Reijneveld,R. Jonas A. Nilsson,R. Jonas A. Nilsson,Bakhos A. Tannous,Pieter Wesseling,Pieter Wesseling,Thomas Wurdinger,Thomas Wurdinger +23 more
TL;DR: The results indicate that blood platelets provide a valuable platform for pan-cancer, multiclass cancer, and companion diagnostics, possibly enabling clinical advances in blood-based “liquid biopsies”.
Journal ArticleDOI
Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up
Linda Douw,Martin Klein,Selene S. A. A. Fagel,Josje van den Heuvel,Martin J.B. Taphoorn,Martin J.B. Taphoorn,Neil K. Aaronson,Tjeerd J. Postma,W. Peter Vandertop,Jacob J. Mooij,Rudolf H. Boerman,Guus Beute,Jasper D. Sluimer,Ben J. Slotman,Jaap C. Reijneveld,Jan J. Heimans +15 more
TL;DR: In this paper, the authors assessed the radiological and cognitive abnormalities in survivors of low-grade glioma (LGG) at a mean of 12 years after first diagnosis.
Journal ArticleDOI
The application of graph theoretical analysis to complex networks in the brain
TL;DR: It is demonstrated through evidence from computational studies, in vivo experiments, and functional MRI, EEG and MEG studies in humans, that both the functional and anatomical connectivity of the healthy brain have many features of a small world network, but only to a limited extent of a scale free network.
Journal ArticleDOI
Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study
Brigitta G. Baumert,Brigitta G. Baumert,Monika E. Hegi,Martin J. van den Bent,Andreas von Deimling,Thierry Gorlia,Khê Hoang-Xuan,Alba A. Brandes,Guy Kantor,Martin J.B. Taphoorn,Mohamed Ben Hassel,Christian Hartmann,Christian Hartmann,Gail Ryan,David Capper,Johan M. Kros,Sebastian Kurscheid,Sebastian Kurscheid,Wolfgang Wick,Roelien H. Enting,Michele Reni,Brian Thiessen,Frédéric Dhermain,Jacoline E C Bromberg,Loïc Feuvret,Jaap C. Reijneveld,Olivier Chinot,J.M.M. Gijtenbeek,John P. Rossiter,Nicolas Dif,Carmen Balana,Jose Bravo-Marques,Paul Clement,Christine Marosi,Tzahala Tzuk-Shina,Robert A Nordal,Jeremy Rees,Denis Lacombe,Warren P. Mason,Roger Stupp,Roger Stupp +40 more
TL;DR: There was no significant difference in outcome of the overall patient population treated with either radiotherapy alone or TMZ chemotherapy alone, and further data maturation is needed for overall survival analyses and evaluation of the full predictive impact of the molecular subtypes for individualized treatment choices.