J
John R. Lake
Researcher at University of Minnesota
Publications - 267
Citations - 22434
John R. Lake is an academic researcher from University of Minnesota. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 75, co-authored 257 publications receiving 20846 citations. Previous affiliations of John R. Lake include University of Virginia & Baylor University Medical Center.
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Journal ArticleDOI
Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.
Shinji Shimoda,Shinji Shimoda,Judith A Van de Water,Aftab A. Ansari,Minoru Nakamura,Hiromi Ishibashi,Ross L. Coppel,John R. Lake,Emmet B. Keeffe,Thomas E. Roche,M. Eric Gershwin +10 more
TL;DR: Results showed a disease-specific 100-150-fold increase in the precursor frequency of PDC-E2 163-176-specific T cells in the hilar lymph nodes and liver when compared with PBMC from PBC patients, providing evidence for a major role for PDC -E2 peptide 163- 176 and/or peptides bearing a similar motif in the pathogenesis of PBC.
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Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure
Steven D. Lidofsky,Nathan M. Bass,Marie Csete Prager,Denna E. Washington,A. E. Read,Teresa L. Wright,Nancy L. Ascher,John P. Roberts,Bruce F. Scharschmidt,John R. Lake +9 more
TL;DR: Intracranial pressure monitoring represents a potentially important tool in the preoperative and intraoperative management of comatose patients with fulminant hepatic failure and warrants further study.
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Hepatic encephalopathy after transjugular intrahepatic portosystemic shunts: incidence and risk factors.
Kenneth A. Somberg,Jonathan L. Riegler,Jeanne M. LaBerge,Margaret M. Doherty‐Simor,Peter Bachetti,John P. Roberts,John R. Lake +6 more
TL;DR: Hepatic encephalopathy is a common complication of TIPS that can be controlled medically in most patients and the identification of clinical variables associated with an increased risk of encephalopathic may be useful in the selection of appropriate candidates for this procedure.
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Early allograft dysfunction after liver transplantation: a definition and predictors of outcome. National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database.
TL;DR: Recipients who develop EAD have longer ICU and hospital stays and greater mortality than those without and a logistic regression model combining donor, graft, and recipient factors predicted EAD better than models examining these factors in isolation.
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Hepatitis C viral infection in liver transplant recipients
TL;DR: In transplant recipients infection by the hepatitis C virus usually produces a mild disease state, but the diagnosis of hepatitis can be difficult to make because indicators of hepatitis may mimic those of rejection, ischemia, obstruction or other hepatic infections.