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Aftab A. Ansari
Researcher at Emory University
Publications - 450
Citations - 24280
Aftab A. Ansari is an academic researcher from Emory University. The author has contributed to research in topics: Primary biliary cirrhosis & Antibody. The author has an hindex of 85, co-authored 446 publications receiving 23007 citations. Previous affiliations of Aftab A. Ansari include Walter and Eliza Hall Institute of Medical Research & Monash University.
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Journal ArticleDOI
Peripartum cardiomyopathy: National Heart, Lung, and Blood Institute and Office of Rare Diseases (National Institutes of Health) workshop recommendations and review.
Gail D. Pearson,Jean-Claude Veille,Shahbudin H. Rahimtoola,Judith Hsia,Celia M. Oakley,Jeffrey D. Hosenpud,Aftab A. Ansari,Kenneth L. Baughman +7 more
TL;DR: Peripartum cardiomyopathy is a rare lethal disease about which little is known and diagnosis is confined to a narrow period and requires echocardiographic evidence of left ventricular systolic dysfunction.
Journal ArticleDOI
A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy
Denise Hilfiker-Kleiner,Karol Kamiński,Edith Podewski,Tomasz A. Bonda,Arnd Schaefer,Karen Sliwa,Olaf Forster,Anja Quint,Ulf Landmesser,Carola Doerries,Maren Luchtefeld,Valeria Poli,Michael D. Schneider,Jean-Luc Balligand,Fanny Desjardins,Aftab A. Ansari,Ingrid Struman,Ngoc Quynh Nhu Nguyen,Nils H. Zschemisch,Gunnar Klein,Gerd Heusch,Rainer Schulz,Andres Hilfiker,Helmut Drexler +23 more
TL;DR: It is shown that female mice with a cardiomyocyte-specific deletion of stat3 develop PPCM, implying that inhibition of prolactin release may represent a novel therapeutic strategy for P PCM.
Journal Article
Cytokine mRNA expression in postischemic/reperfused myocardium.
TL;DR: Results provide evidence for local expression of cytokine mRNA in post-reperfused myocardium and suggest that regulation of local cytokine release is altered during the postischemic period.
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Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium*
Carlo Selmi,Carlo Selmi,David L. Balkwill,Pietro Invernizzi,Aftab A. Ansari,Ross L. Coppel,Mauro Podda,Patrick S.C. Leung,Thomas P. Kenny,Judy Van de Water,Michael H. Nantz,Mark J. Kurth,M. Eric Gershwin +12 more
TL;DR: It is proposed that N. aromaticivorans is a candidate for the induction of PBC, based on protein homology, capacity to metabolize xenobiotics as well as modulate estrogens, its presence in feces, and specific immunologic response.
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Markedly elevated levels of interferon (IFN)-γ, IFN-α, interleukin (IL)-2, IL-10, and tumor necrosis factor-α associated with fatal Ebola virus infection
Francois Villinger,Pierre E. Rollin,Sukhdev S. Brar,Nathaniel F. Chikkala,Jörn Winter,J. Bruce Sundstrom,Sherif R. Zaki,Robert Swanepoel,Aftab A. Ansari,Clarence J. Peters +9 more
TL;DR: It is suggested that a high degree of immune activation accompanies and potentially contributes to a fatal outcome in EHF patients.