J
John Wikstrand
Researcher at Sahlgrenska University Hospital
Publications - 167
Citations - 10395
John Wikstrand is an academic researcher from Sahlgrenska University Hospital. The author has contributed to research in topics: Blood pressure & Heart failure. The author has an hindex of 53, co-authored 167 publications receiving 9930 citations. Previous affiliations of John Wikstrand include AstraZeneca & University of Gothenburg.
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Journal ArticleDOI
Rosuvastatin in Older Patients with Systolic Heart Failure
John Kjekshus,Eduard Apetrei,Vivencio Barrios,Michael Böhm,John G.F. Cleland,Jan H. Cornel,Peter H.J.M. Dunselman,Cândida Fonseca,Assen Goudev,Peer Grande,Lars Gullestad,Åke Hjalmarson,Jaromír Hradec,András Jánosi,Gabriel Kamenský,Michel Komajda,Jerzy Korewicki,Timo Kuusi,François Mach,Vyacheslav Mareev,John J.V. McMurray,Naresh Ranjith,Maria Schaufelberger,Johan Vanhaecke,Dirk J. van Veldhuisen,Finn Waagstein,Hans Wedel,John Wikstrand,John Wikstrand +28 more
TL;DR: Rosuvastatin did not reduce the primary outcome or the number of deaths from any cause in older patients with systolic heart failure, although the drug did reduce the numberOf cardiovascular hospitalizations and the drugdid not cause safety problems.
Journal ArticleDOI
Effects of Controlled-Release Metoprolol on Total Mortality, Hospitalizations, and Well-being in Patients with Heart Failure: The Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
Åke Hjalmarson,Sidney Goldstein Björn Fagerberg,Hans Wredel,Finn Waagstein,John Kjekshus,John Wikstrand,Dia El Allaf,Jirí Vítovec,Jan Aldershivile,M. Halinen,Rainer Dietz,Karl-Ludwig Neuhaus,András Jánosi,Gudmundur Thorgeirsson,Peter H.J.M. Dunselman,Lars Gullestad,J. Kuch,Johan Herlitz,Peter Rickenbacher,Stephen Ball,Stephen S. Gottlieb +20 more
TL;DR: The MERIT-HF Study Group aims to provide real-time information about the physical and social barriers to entry for immigrants to the United States and their impact on the labour market.
Journal ArticleDOI
Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials
Jane Armitage,Colin Baigent,Elizabeth H Barnes,D. John Betteridge,Lisa Blackwell,Michael A. Blazing,Louise Bowman,Eugene Braunwald,Robert P Byington,Christopher P. Cannon,Michael Clearfield,Helen M. Colhoun,Rory Collins,Björn Dahlöf,Kelly Davies,Barry R. Davis,James A. de Lemos,John R. Downs,Paul N. Durrington,Jonathan Emberson,Bengt Fellström,Marcus Flather,Ian Ford,Maria Grazia Franzosi,Jordan Fulcher,John H. Fuller,Curt D. Furberg,David L. Gordon,Shinya Goto,Antonio M. Gotto,Heather Halls,Charlie H.S. Harper,C. Morton Hawkins,William G. Herrington,Graham A. Hitman,Hallvard Holdaas,Lisa Holland,Alan G. Jardine,J. Wouter Jukema,John J.P. Kastelein,Sharon Kean,Anthony C Keech,Adrienne Kirby,John Kjekshus,Genell L. Knatterud,Robert H. Knopp,Wolfgang Koenig,Michael J. Koren,Vera Krane,Martin J Landray,John C. LaRosa,Eva Lonn,Peter W. Macfarlane,Stephen MacMahon,Aldo P. Maggioni,Roberto Marchioli,Ian C. Marschner,Borislava Mihaylova,Lemuel A. Moyé,Sabina A. Murphy,Haruo Nakamura,Andrew Neil,Connie B. Newman,Rachel O'Connell,Chris J. Packard,Sarah Parish,Terje R. Pedersen,Richard Peto,Marc A. Pfeffer,Neil Poulter,David Preiss,Christina Reith,Paul M. Ridker,Michele Robertson,Frank M. Sacks,Naveed Sattar,Roland E. Schmieder,Patrick W. Serruys,Peter S. Sever,John Shaw,Charles L. Shear,John Simes,Peter Sleight,Enti Spata,Luigi Tavazzi,Jonathan A. Tobert,Gianni Tognoni,Andrew Tonkin,Stella Trompet,John Varigos,Christoph Wanner,Hans Wedel,Harvey D. White,John Wikstrand,Lars Wilhelmsen,Kate Wilson,R. Young,Salim Yusuf,Faiez Zannad +98 more
TL;DR: A meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages observed a significant reduction in major vascular events in all age groups.
Journal ArticleDOI
Primary prevention with metoprolol in patients with hypertension. Mortality results from the MAPHY study
TL;DR: Total mortality was significantly lower for metoprolol than for thiazide diuretics because of fewer deaths from coronary heart disease and stroke and the benefit demonstrated in patients treated with metoprole seems to have important implications for clinical practice.
Journal ArticleDOI
Heart rate variability in obesity and the effect of weight loss.
TL;DR: It is suggested that obese patients have increased sympathetic activity and a withdrawal of vagal activity and that these autonomic disturbances improve after weight loss.