Ian C. Marschner

TL;DR: The combined therapies was not significantly superior to either therapy alone, but 10% more patients gained relief with the combination, and the neck pain and effects were maintained.

TL;DR: A meta-analysis of data from all large statin trials to compare the effects of statin therapy at different ages observed a significant reduction in major vascular events in all age groups.

TL;DR: The suppression of plasma HIV RNA after six months of treatment with indinavir, zidovudine, and lamivudine is better sustained by the continuation of these three drugs than by maintenance therapy with either indinavIR alone or zidovo-resistance mutations in HIV RNA at base line.

TL;DR: Changes in lipid levels can explain all or most of the observed benefit of pravastatin and some treatment effect may also be mediated through nonlipid changes.

TL;DR: Data from 1330 human immunodeficiency virus type 1 (HIV-1)-infected patients enrolled in seven antiretroviral treatment trials were analyzed to characterize the clinical benefit of treatment-mediated reductions in plasma HIV-1 RNA levels and indicate that patient prognosis should be assessed using both HIV- 1 RNA and CD4+ lymphocyte responses to therapy.