J
Jonathan P. Whiteley
Researcher at University of Oxford
Publications - 110
Citations - 2738
Jonathan P. Whiteley is an academic researcher from University of Oxford. The author has contributed to research in topics: Finite element method & Nonlinear system. The author has an hindex of 26, co-authored 109 publications receiving 2499 citations. Previous affiliations of Jonathan P. Whiteley include Royal Prince Alfred Hospital.
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Journal ArticleDOI
Chaste: A test-driven approach to software development for biological modelling☆
Joe Pitt-Francis,Pras Pathmanathan,Miguel O. Bernabeu,Rafel Bordas,Jonathan Cooper,Alexander G. Fletcher,Gary R. Mirams,Philip J. Murray,James M. Osborne,Alex Walter,S. Jonathan Chapman,Alan Garny,Ingeborg M.M. van Leeuwen,Philip K. Maini,Blanca Rodriguez,Sarah L. Waters,Jonathan P. Whiteley,Helen M. Byrne,David J. Gavaghan +18 more
TL;DR: Chaste (‘Cancer, heart and soft-tissue environment’) is a software library and a set of test suites for computational simulations in the domain of biology and has been developed using agile programming methods.
Journal ArticleDOI
Multi-scale computational modelling in biology and physiology.
James Southern,Joe Pitt-Francis,Jonathan P. Whiteley,Daniel Stokeley,Hiromichi Kobashi,R. H. Nobes,Yoshimasa Kadooka,David J. Gavaghan +7 more
TL;DR: A definition of multi-scale in terms of levels of biological organisation is formulated and the types of model that are found at each level are described and key issues that arise in trying to formulate and solve multi- scale and multi-physics models are considered.
Journal ArticleDOI
An integrative computational model for intestinal tissue renewal
I.M.M. van Leeuwen,I.M.M. van Leeuwen,Gary R. Mirams,A. Walter,Alexander G. Fletcher,Philip J. Murray,James M. Osborne,Susheel Varma,Sarah Young,Jonathan Cooper,Barney Lee Doyle,Joe Pitt-Francis,Lee Momtahan,Pras Pathmanathan,Jonathan P. Whiteley,Stephen J Chapman,David J. Gavaghan,Oliver E. Jensen,John R. King,Philip K. Maini,Sarah L. Waters,Helen M. Byrne +21 more
TL;DR: A new multiscale model for crypt dynamics is proposed that links phenomena occurring at the subcellular, cellular and tissue levels of organisation to investigate how its dysfunction can lead to loss of homeostasis and neoplasia.
Journal ArticleDOI
Homogenization via formal multiscale asymptotics and volume averaging: How do the two techniques compare?
Yohan Davit,Yohan Davit,Christopher G. Bell,Helen M. Byrne,Lloyd A. C. Chapman,L. S. Kimpton,Georgina E. Lang,Katherine H.L. Leonard,James M. Oliver,Natalie Pearson,Rebecca J. Shipley,Sarah L. Waters,Jonathan P. Whiteley,Brian D. Wood,Michel Quintard,Michel Quintard +15 more
TL;DR: The goal is to bridge the gap between formal multiscale asymptotics and the volume averaging theory and, in so doing, compare their respective advantages/disadvantages from a practical point of view.
Journal ArticleDOI
Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross-correlation
A.B. Rowley,Stephen J. Payne,Ilias Tachtsidis,Mark Ebden,Jonathan P. Whiteley,David J. Gavaghan,Lionel Tarassenko,Martin D. Smith,Clare E. Elwell,D. T. Delpy +9 more
TL;DR: It is proposed that WCC analysis of the relationship between O(2)Hb and MAP provides a useful method of investigating the dynamics of cerebral autoregulation using the spontaneous low-frequency oscillations that are typically observed in both variables without having to make the assumption of stationarity of the time series.