S
Susheel Varma
Researcher at European Bioinformatics Institute
Publications - 23
Citations - 703
Susheel Varma is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Data sharing & Computer science. The author has an hindex of 10, co-authored 19 publications receiving 462 citations. Previous affiliations of Susheel Varma include University of Sheffield.
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Journal ArticleDOI
An integrative computational model for intestinal tissue renewal
I.M.M. van Leeuwen,I.M.M. van Leeuwen,Gary R. Mirams,A. Walter,Alexander G. Fletcher,Philip J. Murray,James M. Osborne,Susheel Varma,Sarah Young,Jonathan Cooper,Barney Lee Doyle,Joe Pitt-Francis,Lee Momtahan,Pras Pathmanathan,Jonathan P. Whiteley,Stephen J Chapman,David J. Gavaghan,Oliver E. Jensen,John R. King,Philip K. Maini,Sarah L. Waters,Helen M. Byrne +21 more
TL;DR: A new multiscale model for crypt dynamics is proposed that links phenomena occurring at the subcellular, cellular and tissue levels of organisation to investigate how its dysfunction can lead to loss of homeostasis and neoplasia.
Journal ArticleDOI
Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis: Results From the VIRTU-Fast Study
Paul Morris,Paul Morris,Daniel Alejandro Silva Soto,Jeroen F.A. Feher,D. Rafiroiu,Angela Lungu,Susheel Varma,Patricia V. Lawford,D. Rodney Hose,Julian Gunn,Julian Gunn +10 more
TL;DR: In this article, two mathematical methods (steady and pseudotransient) were developed that accelerate the computation of vFFR from >36h to <36h using paired steady-state CFD analyses, without the need for computationally expensive, full transient CFD analysis.
Journal ArticleDOI
Federated discovery and sharing of genomic data using Beacons.
Marc Fiume,Miroslav Cupak,Stephen Keenan,Jordi Rambla,Sabela de la Torre,Stephanie O.M. Dyke,Anthony J. Brookes,Knox Carey,David Lloyd,Peter Goodhand,Maximilian Haeussler,Michael Baudis,Michael Baudis,Heinz Stockinger,Lena Dolman,Ilkka Lappalainen,Ilkka Lappalainen,Juha Törnroos,Mikael Linden,J. Dylan Spalding,Saif Ur-Rehman,Angela Page,Paul Flicek,Paul Flicek,Stephen T. Sherry,David Haussler,Susheel Varma,Gary Saunders,Serena Scollen +28 more
TL;DR: The Beacon protocol is described and how it can be used as a model for the federated discovery and sharing of genomic data.
GA4GH: International policies and standards for data sharing across genomic research and healthcare
Heidi L. Rehm,Heidi L. Rehm,Angela Page,Lindsay Smith,Jeremy Adams,Gil Alterovitz,Gil Alterovitz,Lawrence J. Babb,Maxmillian P. Barkley,Michael Baudis,Michael Baudis,Michael J.S. Beauvais,Tim Beck,Jacques S. Beckmann,Sergi Beltran,Sergi Beltran,David Bernick,Alexander Bernier,James K. Bonfield,Tiffany Boughtwood,Guillaume Bourque,Sarion R. Bowers,Anthony J. Brookes,Michael Brudno,Matthew H. Brush,David Bujold,Tony Burdett,Orion J. Buske,Moran N. Cabili,Daniel L Cameron,Daniel L Cameron,Robert J. Carroll,Esmeralda Casas-Silva,Debyani Chakravarty,Bimal Chaudhari,Bimal Chaudhari,Shu Hui Chen,J. Michael Cherry,Justina Chung,Melissa S. Cline,Hayley L. Clissold,Robert Cook-Deegan,Mélanie Courtot,Fiona Cunningham,Miro Cupak,Robert L. Davies,Danielle Denisko,Megan Doerr,Lena I. Dolman,Edward S. Dove,L. Jonathan Dursi,Stephanie O.M. Dyke,James A. Eddy,Karen Eilbeck,Kyle Ellrott,Susan Fairley,Khalid A. Fakhro,Khalid A. Fakhro,Helen V. Firth,Michael S. Fitzsimons,Marc Fiume,Paul Flicek,Ian Fore,Mallory A. Freeberg,Robert R. Freimuth,Lauren A. Fromont,Jonathan Fuerth,Clara L. Gaff,Weiniu Gan,Elena M. Ghanaim,David Glazer,Robert C. Green,Robert C. Green,Malachi Griffith,Obi L. Griffith,Robert L. Grossman,Tudor Groza,Jaime M. Guidry Auvil,Roderic Guigó,Dipayan Gupta,Melissa Haendel,Ada Hamosh,David Hansen,Reece K. Hart,Dean Hartley,David Haussler,Rachele M. Hendricks-Sturrup,Calvin W. L. Ho,Ashley E. Hobb,Michael M. Hoffman,Michael M. Hoffman,Oliver Hofmann,Oliver Hofmann,Petr Holub,Jacob Shujui Hsu,Jean-Pierre Hubaux,Sarah E. Hunt,Ammar Husami,Julius O.B. Jacobsen,Saumya Shekhar Jamuar,Elizabeth L. Janes,Francis Jeanson,Aina Jene,Amber L. Johns,Yann Joly,Steven J.M. Jones,Alexander Kanitz,Alexander Kanitz,Kazuto Kato,Thomas M. Keane,Thomas M. Keane,Kristina Kekesi-Lafrance,Jerome Kelleher,Giselle Kerry,Seik-Soon Khor,Bartha Maria Knoppers,Melissa A. Konopko,Kenjiro Kosaki,Martin Kuba,Jonathan Lawson,Rasko Leinonen,Stephanie Li,Michael F. Lin,Mikael Linden,Xianglin Liu,Isuru Udara Liyanage,Javier Lopez,Anneke M. Lucassen,Michael Lukowski,Alice L. Mann,John F. Marshall,Michele Mattioni,Alejandro Metke-Jimenez,Anna Middleton,Richard Milne,Fruzsina Molnár-Gábor,Nicola Mulder,Monica C. Munoz-Torres,Rishi Nag,Hidewaki Nakagawa,Jamal Nasir,Arcadi Navarro,Tristan H. Nelson,Ania Niewielska,Amy Nisselle,Jeffrey Niu,Tommi Nyrönen,Brian O'Connor,Sabine Oesterle,Soichi Ogishima,Vivian Ota Wang,Laura A.D. Paglione,Emilio Palumbo,Helen Parkinson,Anthony A. Philippakis,Angel Pizarro,Andreas Prlic,Jordi Rambla,Augusto Rendon,Renee A. Rider,Peter N. Robinson,Kurt W. Rodarmer,Laura Lyman Rodriguez,Alan F. Rubin,Alan F. Rubin,Manuel Rueda,Gregory A. Rushton,Rosalyn S. Ryan,Gary I. Saunders,Helen Schuilenburg,Torsten Schwede,Torsten Schwede,Serena Scollen,Alexander Senf,Nathan C. Sheffield,Neerjah Skantharajah,Albert V. Smith,Heidi J. Sofia,Dylan Spalding,Amanda B. Spurdle,Zornitza Stark,Lincoln Stein,Lincoln Stein,Makoto Suematsu,Patrick Tan,Patrick Tan,Jonathan A. Tedds,Alastair A. Thomson,Adrian Thorogood,Adrian Thorogood,Timothy L. Tickle,Katsushi Tokunaga,Juha Törnroos,David Torrents,David Torrents,Sean Upchurch,Alfonso Valencia,Alfonso Valencia,Roman Valls Guimera,Jessica Vamathevan,Susheel Varma,Danya F. Vears,Coby Viner,Coby Viner,Craig Voisin,Alex H. Wagner,Alex H. Wagner,Susan E. Wallace,Brian Walsh,Marc S. Williams,Eva C. Winkler,Barbara J. Wold,Grant M. Wood,J. Patrick Woolley,Chisato Yamasaki,Andrew D. Yates,Christina K. Yung,Lyndon J. Zass,Ksenia Zaytseva,Junjun Zhang,Peter Goodhand,Kathryn North,Kathryn North,Ewan Birney +223 more
TL;DR: The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches.
Journal ArticleDOI
Leveraging European infrastructures to access 1 million human genomes by 2022
Gary Saunders,Michael Baudis,Regina Becker,Sergi Beltran,Christophe Béroud,Ewan Birney,Cath Brooksbank,Søren Brunak,Søren Brunak,Marc Van den Bulcke,Rachel Drysdale,Salvador Capella-Gutierrez,Paul Flicek,Francesco Florindi,Peter Goodhand,Ivo Gut,Jaap Heringa,Petr Holub,Jef Hooyberghs,Nick Juty,Thomas Keane,Jan O. Korbel,Ilkka Lappalainen,Brane Leskošek,Gert Matthijs,Michaela Th. Mayrhofer,Andres Metspalu,Arcadi Navarro,Arcadi Navarro,Steven Newhouse,Tommi Nyrönen,Angela Page,Bengt Persson,Aarno Palotie,Helen Parkinson,Jordi Rambla,David Salgado,Erik Steinfelder,Morris A. Swertz,Alfonso Valencia,Susheel Varma,Niklas Blomberg,Serena Scollen +42 more
TL;DR: This Roadmap identifies the challenges of data sharing across borders and demonstrates that European research infrastructures are well-positioned to support the rapid implementation of widespread genomic data access.