J
Jonathan Z. Long
Researcher at Stanford University
Publications - 83
Citations - 12581
Jonathan Z. Long is an academic researcher from Stanford University. The author has contributed to research in topics: JZL184 & Fatty acid amide hydrolase. The author has an hindex of 37, co-authored 69 publications receiving 10665 citations. Previous affiliations of Jonathan Z. Long include Kettering University & Harvard University.
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Journal ArticleDOI
An exercise-inducible metabolite that suppresses feeding and obesity
Veronica L. Li,Yang He,Kévin Contrepois,Hailan Liu,Joon T. Kim,Amanda L Wiggenhorn,Julia T. Tanzo,A. Tung,Xuchao Lyu,Peter-James H. Zushin,Robert S. Jansen,Basil Michael,Kang Yong Loh,Andrew C. Yang,Christian S. Carl,Christian T. Voldstedlund,Wei Wei,Stephanie M. Terrell,Benjamin C. Moeller,Rick M. Arthur,Gareth A. Wallis,Koen van de Wetering,Andreas Stahl,Bente Kiens,Erik A. Richter,Steven M. Banik,Michael Snyder,Yong Xu,Jonathan Z. Long +28 more
TL;DR: In this paper , the authors show that exercise stimulates the production of N-lactoyl-phenylalanine (Lac-Phe), a blood-borne signalling metabolite that suppresses feeding and obesity.
Journal ArticleDOI
Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats
Martin A. Sticht,Jonathan Z. Long,Erin M. Rock,Cheryl L. Limebeer,Raphael Mechoulam,Benjamin F. Cravatt,Linda A. Parker +6 more
TL;DR: The role of 2‐arachidonoyl glycerol (2AG) in the regulation of nausea and vomiting using animal models of vomiting and of nausea‐like behaviour (conditioned gaping) is evaluated.
Journal ArticleDOI
An exercise-inducible metabolite that suppresses feeding and obesity
Veronica L. Li,Yang He,Kévin Contrepois,Hailan Liu,Joon T. Kim,Amanda L Wiggenhorn,Julia T. Tanzo,A. Tung,Xuchao Lyu,Peter-James H. Zushin,Robert S. Jansen,Basil Michael,Kang Yong Loh,Andrew C. Yang,Christian S. Carl,Christian T. Voldstedlund,Wei Wei,Stephanie M. Terrell,Benjamin C. Moeller,Rick M. Arthur,Gareth A. Wallis,Koen van de Wetering,Andreas Stahl,Bente Kiens,Erik A. Richter,Steven M. Banik,Michael Snyder,Yong Xu,Jonathan Z. Long +28 more
TL;DR: In this paper , the authors show that exercise stimulates the production of N-lactoyl-phenylalanine (Lac-Phe), a blood-borne signalling metabolite that suppresses feeding and obesity.
Journal ArticleDOI
Reversible Competitive α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Constraints in the Acyl Side Chain: Orally Active, Long Acting Analgesics
Cyrine Ezzili,Mauro Mileni,Nicholas McGlinchey,Jonathan Z. Long,Steven G. Kinsey,Dustin G. Hochstatter,Raymond C. Stevens,Aron H. Lichtman,Benjamin F. Cravatt,Edward J. Bilsky,Dale L. Boger +10 more
TL;DR: Preliminary in vivo characterization of the inhibitors 12 and 14 is reported demonstrating that they raise brain anandamide levels following either intraperitoneal (ip) or oral (po) administration indicative of effective in vivo FAAH inhibition.
Journal ArticleDOI
Cell type-selective secretome profiling in vivo.
Wei Wei,Nicholas M. Riley,Andrew C. Yang,Joon T. Kim,Stephanie M. Terrell,Veronica L. Li,Marta Garcia-Contreras,Carolyn R. Bertozzi,Carolyn R. Bertozzi,Jonathan Z. Long +9 more
TL;DR: A proximity biotinylation strategy that enables labeling, detection and enrichment of secreted polypeptides in a cell type-selective manner in mice and generates a proteomic atlas of hepatocyte, myocyte, pericyte and myeloid cell secretomes by direct purification ofBiotinylated secreted proteins from blood plasma.