J
Jong Woo Kim
Researcher at Electronics and Telecommunications Research Institute
Publications - 24
Citations - 377
Jong Woo Kim is an academic researcher from Electronics and Telecommunications Research Institute. The author has contributed to research in topics: Thin-film transistor & Oxide thin-film transistor. The author has an hindex of 10, co-authored 24 publications receiving 311 citations. Previous affiliations of Jong Woo Kim include Myongji University.
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Journal ArticleDOI
The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo
Wei Gao,Jin Yong Kim,Jeffrey R. Anderson,Tatos Akopian,Seungpyo Hong,Ying Yu Jin,Olga Kandror,Jong Woo Kim,In Ae Lee,Sun-Young Lee,James B. McAlpine,Surafel Mulugeta,Suhair Sunoqrot,Yuehong Wang,Seung Hwan Yang,Tae Mi Yoon,Alfred L. Goldberg,Guido F. Pauli,Joo Won Suh,Scott G. Franzblau,Sang-Hyun Cho +20 more
TL;DR: Genome mining of lab-generated, spontaneous ecumicin-resistant M. tuberculosis strains identified the ClpC1 ATPase complex as the putative target, and this was confirmed by a drug affinity response test, and ecumICin may serve as a lead compound for anti-TB drug development.
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Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice.
Tae-Won Kim,In-Bae Song,Hong-Ki Lee,Jong-Hwan Lim,Eun-Sang Cho,Hwa-Young Son,Sang-Jin Park,Jong Woo Kim,Hyo-In Yun +8 more
TL;DR: In histopathological examination, pretreatment with PD showed ameliorated renal injury such as intraluminal cast formation and epithelial desquamation and over-expression of nuclear factor-kappa B p65 and apoptotic cells were suppressed by PD pretreatment.
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Triterpenoid Saponins Isolated from Platycodon grandiflorum Inhibit Hepatitis C Virus Replication.
Jong Woo Kim,Sang Jin Park,Jong Hwan Lim,Jae Won Yang,Jung Cheul Shin,Sang-wook Lee,Joo Won Suh,Soon B. Hwang +7 more
TL;DR: It is demonstrated that combinatorial treatment of PGSM and IFN-α efficiently suppressed colony formation with significant reduction in drug resistant variant of HCV, suggesting that triterpenoid saponin may represent a novel anti-HCV therapeutic agent.
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An efficient approach for cloning the dNDP‐glucose synthase gene from actinomycetes and its application in Streptomyces spectabilis, a spectinomycin producer
TL;DR: By DNA sequence analysis, seven amplified fragments showed high homology with dTDP-glucose synthase genes that participate in the biosynthesis of secondary metabolites or in deoxy-sugar moieties in lipopolysaccharides.
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Talosins A and B: new isoflavonol glycosides with potent antifungal activity from Kitasatospora kifunensis MJM341. I. Taxonomy, fermentation, isolation, and biological activities.
TL;DR: These talosins are the first isoflavonol glycosides with a 6-deoxy-talose sugar component and they may be useful as antifungal agents with low toxicity because of no visible cytotoxicity against the human hepatic HepG2 cell.