J
Joost Witlox
Publications - 18
Citations - 2768
Joost Witlox is an academic researcher. The author has contributed to research in topics: Delirium & Hip fracture. The author has an hindex of 12, co-authored 17 publications receiving 2453 citations.
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Journal ArticleDOI
Delirium in Elderly Patients and the Risk of Postdischarge Mortality, Institutionalization, and Dementia: A Meta-analysis
Joost Witlox,Lisa S. M. Eurelings,Jos F. M. de Jonghe,Kees J. Kalisvaart,Piet Eikelenboom,Willem A. van Gool +5 more
TL;DR: Evidence is provided that delirium in elderly patients is associated with poor outcome independent of important confounders, such as age, sex, comorbid illness or illness severity, and baseline dementia.
Delirium in Elderly Patients and the Risk of Postdischarge Mortality, Institutionalization, and Dementia
Joost Witlox,Lisa S. M. Eurelings,Jos F. M. de Jonghe,Kees J. Kalisvaart,Piet Eikelenboom,Willem A. van Gool +5 more
TL;DR: Eurelings et al. as discussed by the authors found that older patients with delirium experienced increased long-term mortality in one study, but not in another, which may affect conclusions.
Journal ArticleDOI
Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients
Dunja Westhoff,Joost Witlox,Leo Koenderman,Kees J. Kalisvaart,Jos F. M. de Jonghe,Mireille F. M. van Stijn,Alexander P. J. Houdijk,Inge C M Hoogland,Alasdair M.J. MacLullich,David J. van Westerloo,Diederik van de Beek,Piet Eikelenboom,Willem A. van Gool +12 more
TL;DR: The findings fit the hypothesis that delirium after surgery results from a dysfunctional neuroinflammatory response: stressing the role of reduced levels of anti-inflammatory mediators in this process.
Journal ArticleDOI
Cerebrospinal fluid β-amyloid and tau are not associated with risk of delirium: a prospective cohort study in older adults with hip fracture.
Joost Witlox,Kees J. Kalisvaart,Jos F. M. de Jonghe,Nicolaas A. Verwey,Mireille F. M. van Stijn,Alexander P. J. Houdijk,Han S. Traast,Alasdair M.J. MacLullich,Willem A. van Gool,Piet Eikelenboom +9 more
TL;DR: The association between cerebrospinal fluid β‐amyloid (Aβ1–42), tau, and hyperphosphorylated tau (Ptau) and risk of delirium in older adults with hip fracture is examined.
Journal ArticleDOI
Delirium detection using relative delta power based on 1-minute single-channel EEG: a multicentre study.
T. Numan,M van den Boogaard,A. M. Kamper,Paul J.T. Rood,Linda M. Peelen,AJ Slooter,Masieh Abawi,Mark van den Boogaard,Jurgen A.H.R. Claassen,Michael Coesmans,Paul L. J. Dautzenberg,Ton A. Df. Dhondt,Shiraz B. Diraoui,P. Eikelenboom,Marielle H. Emmelot-Vonk,Richard A. Faaij,Willem A. van Gool,Erwin R. Groot,Carla Hagestein-de Bruijn,Jacqueline G. F. M. Hovens,Mathieu van der Jagt,Annemarieke de Jonghe,Adriaan M. Kamper,Huiberdine L. Koek,Arendina W. van der Kooi,Marjan Kromkamp,Joep Lagro,Albert F.G. Leentjens,Geert J. Lefeber,Frans S. S. Leijten,Carsten Leue,Tjarda de Man,Robert J. van Marum,Robert J. van Marum,Roos C. van der Mast,Roos C. van der Mast,Barbara C. van Munster,Tianne Numan,Robert Jan Osse,C. Barbara Portier,Nathaly Rius Ottenheim,Paul J T Rood,Christian H. Röder,Yvonne Schoon,Arjen J. C. Slooter,Arjen Tromp,Joris B. van der Vlugt,Ariël M. Vondeling,Annelies Wassenaar,Henry C. Weinstein,Joost Witlox,Jeroen S. van Zanten,Philip M. Zeman,Sanneke van der Zwaag +53 more
TL;DR: Delirium/possible delirium can be detected in older postoperative patients based on a single‐channel EEG recording that can be automatically analysed, and this objective detection method with a continuous scale instead of a dichotomised outcome is a promising approach for routine detection of deliria.