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Jörg D. Hoheisel

Researcher at German Cancer Research Center

Publications -  205
Citations -  10176

Jörg D. Hoheisel is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Pancreatic cancer & Gene. The author has an hindex of 47, co-authored 196 publications receiving 9398 citations. Previous affiliations of Jörg D. Hoheisel include Merck & Co..

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Versatile derivatisation of solid support media for covalent bonding on DNA-microchips

TL;DR: A chemistry was developed that permits on DNA-arrays both the covalent immobilisation of pre-fabricated nucleic acids-such as oligonucleotides, PCR-products or peptide nucleic acid oligomers-and the in situ synthesis of such compounds on either glass or polypropylene surfaces.
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Correspondence analysis applied to microarray data

TL;DR: This work demonstrates the applicability of correspondence analysis to and high value for the analysis of microarray data, displaying associations between genes and experiments and applies it to a non-time-series data set of its own.
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Solid supports for microarray immunoassays

TL;DR: The sensitivity of microspot immunoassays predicted by the current analyte theory is not yet a reality, indicating the extent of both the technology's potential and the size of the task still ahead.
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Hybridisation based DNA screening on peptide nucleic acid (PNA) oligomer arrays

TL;DR: Successful discrimination between hybridisation to full complementary PNA sequences and truncated or mismatched versions was possible at salt concentrations down to 10 mM Na+and below, although an increasing tendency to unspecific DNA binding and few strong mismatch hybridisation events were observed.