Joseph C. Burns

TL;DR: Comparisons of cell types from utricles and cochleae demonstrate divergence between auditory and vestibular cells, despite a common origin, and suggest possible plasticity among cells at the sensory–nonsensory boundary.

TL;DR: Single cell RNAseq analysis is used to provide insight into the transcriptional changes arising during development of the murine cochlear inner and outer hair cells to provide insights regarding cochLear development.

TL;DR: Findings show that regeneration limits arise in vivo during the postnatal period when the mammalian balance epithelium's supporting cells differentiate unique cytological characteristics and lose plasticity, and they support the notion that the differentiation of those cells may directly inhibit regeneration or eliminate an essential, but as yet unidentified pool of stem cells.

TL;DR: Hair cell populations in neonatal mouse utricles grow appreciably through two processes: the progressive differentiation of cells generated before birth and the differentiation of new cells arising from divisions of progenitors that progress through S phase soon after birth.

TL;DR: Vestibular sensation is essential for gaze stabilization, balance, and perception of gravity in humans as discussed by the authors, and it can cause crippling symptoms such as vertigo, visual field oscillation, and imbalance.