J
Joseph C. Corbo
Researcher at Washington University in St. Louis
Publications - 94
Citations - 8604
Joseph C. Corbo is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Enhancer & Gene. The author has an hindex of 38, co-authored 91 publications receiving 7676 citations. Previous affiliations of Joseph C. Corbo include Brigham and Women's Hospital & Stanford University.
Papers
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Journal ArticleDOI
Transcriptional Regulation of Neural Retina Leucine Zipper (Nrl), a Photoreceptor Cell Fate Determinant
Cynthia L. Montana,Karen A. Lawrence,Natecia L. Williams,Nicholas M. Tran,G.-H. Peng,Shiming Chen,Joseph C. Corbo +6 more
TL;DR: The results indicate that CRX, OTX2, and RORβ directly regulate Nrl transcription by binding to critical sites within the Nrl promoter.
Journal ArticleDOI
A complex carotenoid palette tunes avian colour vision.
Matthew B. Toomey,Aaron M. Collins,Rikard Frederiksen,M. Carter Cornwall,Jerilyn A. Timlin,Joseph C. Corbo +5 more
TL;DR: This study integrated results from high-performance liquid chromatography, hyperspectral microscopy and microspectrophotometry to obtain a comprehensive understanding of oil droplet carotenoid pigmentation in the chicken.
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Complementary shifts in photoreceptor spectral tuning unlock the full adaptive potential of ultraviolet vision in birds
Matthew B. Toomey,Olle Lind,Rikard Frederiksen,Robert W. Curley,Ken M. Riedl,David Wilby,Steven J. Schwartz,Christopher C. Witt,Earl H. Harrison,Nicholas W. Roberts,Misha Vorobyev,Kevin J. McGraw,M. Carter Cornwall,Almut Kelber,Joseph C. Corbo +14 more
TL;DR: An enzymatic pathway that mediates the differential production of these apocarotenoids in the avian retina is proposed, and color vision modeling is used to demonstrate how correlated evolution of spectral tuning is necessary to achieve even sampling of the light spectrum and thereby maintain near-optimal color discrimination.
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Evolution, Development and Function of Vertebrate Cone Oil Droplets.
TL;DR: The occurrence and properties of oil droplets across the diversity of vertebrate species are surveyed and what these patterns indicate about the evolutionary history and function of this intriguing organelle is discussed.
Journal ArticleDOI
Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes involved in avian photoreceptor diversification.
TL;DR: Hundreds of differentially expressed genes are identified involved in a variety of processes, including phototransduction, transcriptional regulation, cell adhesion, maintenance of intra‐ and extracellular structure, and metabolism in avian photoreceptor subtypes.